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      Penfigoide ampolloso secundario a vildagliptina Translated title: Bullous pemphigoid secondary to vildagliptin

      case-report

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          Abstract

          RESUMEN El penfigoide ampolloso es una enfermedad autoinmune caracterizada por presencia de lesiones urticariformes o eccematosas muy pruriginosas sobre las que posteriormente pueden aparecer ampollas tensas de contenido seroso o hemorrágico. Planteamos un caso clínico de un paciente con penfigoide ampolloso secundario a vildagliptina. Aunque el diagnóstico definitivo se realiza mediante dos biopsias cutáneas, en nuestro caso, dada la alta sospecha clínica, comenzamos con tratamiento con corticoides y suspendimos la vidagliptina con resolución del cuadro en pocas semanas. Nos parece interesante no solo por el diagnóstico en sí, sino también para destacar la importancia del papel del médico de familia en este tipo de enfermedades tanto a nivel del diagnóstico como del seguimiento de la evolución y del tratamiento. Y por otra parte para resaltar la utilidad de las nuevas tecnologías, como la teledermatología.

          Translated abstract

          ABSTRACT Bullous pemphigoid is an autoimmune disease characterised by presence of very pruritic hives-like or eczema-like lesions on top of which serum- or blood-containing tense blisters can later appear. We present the clinical case of a patient with bullous pemphigoid secondary to vildagliptin. Although the definitive diagnosis is made by two skin biopsies, in this case, given high clinical suspicion, we began treatment with corticosteroids and discontinued vildagliptin, with complete resolution in a few weeks. This case is interesting not only for its diagnosis, but also to highlight the importance of the role of the family doctor in this type of diseases, in diagnosis and in the follow-up and treatment. And also to emphasise the usefulness of new technologies, like teledermatology.

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          Most cited references5

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          Dipeptidyl peptidase IV inhibitors, a risk factor for bullous pemphigoid: Retrospective multicenter case-control study from France and Switzerland

          Case reports have suggested an association between dipeptidyl peptidase-4 inhibitors (DPP4is) and development of bullous pemphigoid (BP).
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            Penfigoide ampolloso:guía de manejo práctico

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              Association of bullous pemphigoid with dipeptidyl-peptidase 4 inhibitors in patients with diabetes: estimating the risk of the new agents and characterizing the patients

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                Author and article information

                Journal
                albacete
                Revista Clínica de Medicina de Familia
                Rev Clin Med Fam
                Sociedad Castellano-Manchega de Medicina de Familia y Comunitaria (Albacete, Castilla La Mancha, Spain )
                1699-695X
                2386-8201
                2020
                : 13
                : 2
                : 162-165
                Affiliations
                [2] Toledo orgnameCentro de Salud de Santa María de Benquerencia España
                [1] Toledo orgnameCentro de Salud de Santa María de Benquerencia España
                Article
                S1699-695X2020000200012 S1699-695X(20)01300200012
                24ba718a-a388-4c8d-8ecd-3595aaa42a55

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

                History
                : 05 June 2019
                : 10 April 2019
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 6, Pages: 4
                Product

                SciELO Spain

                Categories
                Un paciente con...

                Telemedicine,Inhibidores de la Dipeptidil-Peptidasa IV,Dipeptidyl-Peptidase IV Inhibitors,Pemphigoid, Bullous,Penfigoide Ampolloso,Medicina Familiar y Comunitaria,Telemedicina,Family Practice

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