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The immune contexture in human tumours: impact on clinical outcome
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Abstract
Tumours grow within an intricate network of epithelial cells, vascular and lymphatic
vessels, cytokines and chemokines, and infiltrating immune cells. Different types
of infiltrating immune cells have different effects on tumour progression, which can
vary according to cancer type. In this Opinion article we discuss how the context-specific
nature of infiltrating immune cells can affect the prognosis of patients.