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      Effect of corticosterone on the prolactin response to psychological and physical stress in rats

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      Life Sciences

      Elsevier BV

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          Most cited references 15

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          The general adaptation syndrome and the diseases of adaptation.

           H Selye (1946)
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            Stress response patterns of plasma corticosterone, prolactin, and growth hormone in the rat, following handling or exposure to novel environment.

             J Seggie,  G. M. Brown (1975)
            Corticosterone, prolactin, and growth hormone responses to 5 s of handling or 3 min of novel environment were compared in rats at crest and trough of the diurnal adrenal rhythm 0, 5, 15, 30, and 60 min after stimulation. All hormones responded to stimulation, corticosterone and prolactin with a dramatic rise, and growth hormone with a precipitous fall. Resting corticosterone levels evidenced the expected diurnal variation, and prolactin but not growth hormone also showed a baseline diurnal variation of small magnitude at the times studied. Growth hormone response characteristics were unaffected by time of day or type of stimulation. Both corticosterone and prolactin response profiles differed at both times of day and following both types of stimulation. Corticosterone and prolactin levels were highly correlated and each was negatively correlated with growth hormone levels. This study confirms that hormone responses to stress are complex and depend not only on the stimulus but the context of stimulation.
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              The Effects of Acute Stress on the Secretion of LH, FSH, Prolactin and GH in the Normal Male Rat, with Comments on Their Statistical Evaluation

               L Krulich,  E Hefco,  P Illner (1974)
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                Author and article information

                Journal
                Life Sciences
                Life Sciences
                Elsevier BV
                00243205
                October 1984
                October 1984
                : 35
                : 16
                : 1705-1711
                Article
                10.1016/0024-3205(84)90183-8
                © 1984

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