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      Safety of intravenous thrombolysis in stroke mimics: prospective 5-year study and comprehensive meta-analysis.

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          Abstract

          Shortening door-to-needle time may lead to inadvertent intravenous thrombolysis (IVT) administration in stroke mimics (SMs). We sought to determine the safety of IVT in SMs using prospective, single-center data and by conducting a comprehensive meta-analysis of reported case-series.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Stroke
          Title: Stroke
          Publisher: Ovid Technologies (Wolters Kluwer Health)
          ISSN (Electronic): 1524-4628
          ISSN (Print): 0039-2499
          Publication date (Electronic): May 2015
          Volume: 46
          Issue: 5
          Affiliations
          [1 ] From the Department of Neurology, University of Tennessee Health Science Center, Memphis (G.T., R.Z., N.G., J.C., A.W.A., M.D.M., A.V.A.); Second Department of Neurology, "Attikon University Hospital," School of Medicine, University of Athens, Athens, Greece (G.T., A.H.K.); Department of Neurology, Cerebrovascular Center, Cleveland Clinic, OH (K.U.); Department of Neurology, University Hospital of Larissa, University of Thessaly, Larissa, Greece (E.D.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (J.P.); and College of Nursing, Australian Catholic University, Sydney, New South Wales, Australia (A.W.A.).
          Article
          Publisher Item ID: STROKEAHA.115.009012
          DOI: 10.1161/STROKEAHA.115.009012
          PubMed ID: 25791717
          SO-VID: 255cd9fa-1d38-4f99-81e1-7a72a1a0cdca
          History

          Keywords: intracranial hemorrhages,misdiagnosis,safety,stroke,tissue-type plasminogen activator
          Data availability:
          Keywords: intracranial hemorrhages, misdiagnosis, safety, stroke, tissue-type plasminogen activator

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