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      Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015

      abstract
      1 , , 2 , 2 , 3 , 3 , 3 , 2 , 3 , , 4 , 4 , 5 , 6 , 7 , , 8 , 8 , , 8 , 8 , 8 , 8 , 8 , 8 , 8 , 8 , 8 , 8 , 8 , 8 , 8 , 8 , 8 , 9 , , 10 , , 10 , 10 , 10 , 11 , , 12 , , 13 , 14 , , 14 , 14 , 15 , , 16 , , 16 , 17 , 18 , , 18 , 18 , 19 , 20 , 21 , , 22 , , 22 , 22 , 22 , 22 , 22 , 22 , 23 , 24 , , 25 , 26 , , 27 , 28 , , 27 , 27 , 28 , 29 , 29 , 30 , 28 , 31 , 28 , 32 , ,   33 , 34 , , 33 , 34 , 33 , 34 , 35 , 33 , 33 , 33 , 33 , 33 , 34 , 33 , 34 , 33 , 34 , 36 , , 37 , 38 , , 39 , 39 , 40 , 41 , , 42 , 43 , 44 , 45 , 43 , 44 , 43 , 44 , 46 , 46 , 47 , 48 , 47 , 45 , 49 , 43 , , 50 , , 50 , 50 , 50 , 50 , 50 , 51 , , 51 , 52 , 52 , 53 , 54 , 55 , 55 , 56 , 57 , 55 , , 55 , 58 , 59 , , 58 , 59 , 58 , 59 , 60 , 60 , 61 , 58 , 62 , 62 , , 63 , , 63 , 63 , 63 , 64 , 63 , 65 , 66 , , 67 , 68 , 69 , 66 , 70 , 71 , 72 , , 71 , 71 , 72 , 73 , 74 , 71 , 75 , , 75 , 76 , 77 , , 78 , 79 , 80 , 81 , , 80 , 80 , 81 , 82 , 83 , , 83 , 83 , 83 , 83 , 84 , 85 , , 84 , 86 , 84 , 87 , , 88 , 88 , 89 , 90 , 91 , 92 , , 93 , 94 , , 93 , 93 , 93 , 93 , 93 , 93 , 93 , 93 , 93 , 93 , 93 , 93 , 93 , 93 , 93 , 93 , 95 , 95 , 95 , 95 , 96 , 95 , , 97 , , 97 , 97 , 97 , 97 , 97 , 97 , 97 , 97 , 97 , 98 , 98 , 99 , , 100 , 99 , 101 , 102 , , 102 , 102 , 102 , 103 , 103 , 102 , 104 , 105 , , 105 , 106 , 105 , 105 , 107 , 108 , , 108 , 108 , 108 , 108 , 108 , 108 , 108 , 108 , 108 , 108 , 109 , 109 , , 110 , 111 , , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 115 , 117 , , 118 , 119 , 119 , 120 , 118 , 121 , 122 , 122 , 118 , 121 , 119 , 123 , 118 , 119 , 123 , , 477 , 124 , , 124 , 124 , 124 , 124 , 125 , 124 , 126 , 127 , 127 , 128 , , 129 , 130 , 130 , , 131 , , 131 , 132 , 132 , 133 , 134 , 135 , 136 , 134 , 137 , 134 , 137 , 135 , 136 , 134 , 135 , , 138 , 138 , , 138 , 138 , 138 , 138 , 138 , 139 , 140 , , 140 , 140 , 140 , 141 , 140 , 142 , 142 , , 142 , 143 , 142 , 144 , 145 , 146 , 145 , 146 , 147 , 145 , 146 , 145 , 148 , , 148 , 148 , 149 , 148 , 150 , 151 , 152 , 151 , 152 , 151 , 151 , 152 , 153 , 154 , 155 , 154 , , 154 , 154 , 156 , 157 , 158 , 157 , 158 , 157 , 158 , 157 , 159 , 159 , 159 , 159 , 159 , 160 , 160 , 161 , 159 , 159 , , 159 , 162 , , 162 , 163 , 163 , 164 , 165 , 166 , 162 , 162 , 162 , 162 , 162 , 162 , 162 , 162 , 167 , 168 , , 167 , 168 , 169 , 170 , 171 , 172 , 173 , , 174 , , 174 , 175 , 174 , 176 , 177 , 177 , 177 , 177 , 177 , 177 , 178 , 178 , 179 , 180 , 180 , 180 , 180 , 180 , 180 , 181 , 181 , , 181 , 181 , 181 , 181 , 182 , 181 , 183 , 184 , 185 , , 183 , 184 , 185 , 186 , 185 , 187 , 185 , 187 , 188 , 184 , 184 , 189 , 190 , 190 , 191 , 191 , 192 , , 193 , 193 , 194 , 195 , 196 , 195 , 197 , 195 , 197 , 198 , 196 , 195 , 196 , , 199 , 200 , 201 , 201 , 202 , 200 , 203 , , 204 , 204 , 204 , 204 , 204 , 205 , , 204 , 204 , 206 , 206 , 206 , 206 , 206 , 207 , , 206 , 206 , 208 , , 209 , 210 , 209 , 209 , 210 , 209 , 210 , 209 , 211 , 212 , , 213 , 213 , 213 , 213 , 214 , 215 , 216 , 216 , 216 , 216 , 213 , 216 , , 217 , 218 , , 217 , 217 , 218 , 217 , 218 , 219 , 217 , 220 , 217 , 217 , 218 , 221 , , 221 , 222 , 222 , 223 , 224 , 221 , 225 , 221 , 221 , 221 , 221 , 221 , 221 , 221 , 221 , 226 , 227 , 227 , 228 , 228 ,   227 , 229 , 229 , 227 , 227 , 227 , 227 , , 227 , 230 , 230 , 230 , 230 , 230 , 230 , 230 , 230 , , 230 , 231 , 232 , 233 , 232 , , 232 , 234 , 235 , , 235 , 234 , 235 , 236 , , 236 , 237 , 238 , 239 , 236 , 236 , 236 , 240 , 236 , 237 , 238 , 241 , , 241 , 242 , 242 , 242 , 242 , 242 , 243 , 244 , 245 , , 243 , 244 , 245 , 243 , 244 , 246 , 246 , , 246 , 247 , , 247 , 248 , 247 , 247 , 247 , 249 , 249 , 247 , 250 , 250 , 251 , 250 , 250 , 250 , 250 , 250 , , 250 , 252 , 252 , 252 , 252 , 252 , 252 , 252 , 252 , 253 , 254 , 255 , , 252 , 256 , , 256 , 257 , 256 , 258 , 256 , 256 , 256 , 259 , 256 , 256 , 260 , 260 , 261 , 261 , 261 , , 262 , 263 , 263 , 264 , 264 , 265 , 265 , 264 , 266 , 266 , 264 , 264 , 264 , , 267 , 268 , 269 , 268 , 270 , 268 , , 271 , 272 , , 271 , 272 , 272 , 273 , 271 , 271 , 271 , 272 , 274 , 275 , , 275 , 275 , 275 , 276 , 275 , 277 , 277 , 278 , , 278 , 279 , 278 , 280 , 281 , 281 , 281 , 281 , 278 , 281 , 282 , 278 , 283 , , 284 , 283 , 283 , 283 , 283 , 283 , 283 , 283 , 285 , 283 , 286 , 286 , 287 , 287 , 288 , 289 , 290 , 287 , 287 , , 287 , 291 , 294 , , 291 , 292 , 292 , 293 , 295 , 295 , 296 , , 297 , 296 , 295 , 296 , 298 , 299 , , 299 , 299 , 300 , 299 , 301 , 302 , 303 , 304 , , 304 , 305 , , 306 , 305 , 307 , 308 , 309 , 310 , 311 , 309 , , 309 , 309 , 310 , 311 , 312 , 313 , 309 , 314 , 314 , 314 , 315 , 314 , , 314 , 316 , 317 , 316 , 317 , 316 , 316 , 316 , 316 , 316 , , 316 , 318 , , 318 , 319 , 320 , 320 , 321 , 322 , 323 , 321 , 324 , 321 , , 321 , 325 , 325 , 326 , 327 , 325 , 328 , 325 , 328 , 325 , 325 , 325 , 325 , 325 , 325 , 325 , 325 , , 325 , 329 , 330 , 329 , , 329 , 331 , 331 , 332 , 331 , 329 , 330 , 329 , 329 , 329 , 333 , 333 , 333 , 333 , 334 , 335 , 334 , 333 , , 336 , 337 , 336 , 337 , 338 , 337 , 339 , 337 , 339 , 337 , 339 , 340 , 341 , 342 , 337 , 341 , 337 , 343 , 344 , 337 , 341 , , 337 , 345 , 346 , 346 , , 346 , 347 , 348 , 349 , 347 , , 347 , 350 , 351 , 352 , 352 , 353 , 352 , 353 , 352 , 353 , , 354 , , 355 , 354 , 355 , 356 , , 356 , 356 , 357 , 357 , , 358 , 358 , 359 , 359 , 359 , 359 , 360 , 361 , 362 , 362 , 362 , 363 , 360 , 363 , 359 , 359 , , 360 , 364 , 365 , , 365 , 365 , 366 , 367 , 368 , 369 , 368 , 369 , 369 , 368 , 370 , 370 , , 370 , 371 , , 371 , 371 , 371 , 372 , 373 , , 373 , 374 , 375 , 376 , 377 , 372 , 378 , 379 , 380 , 381 , 382 , 378 , , 378 , 378 , 379 , 380 , 381 , 382 , 383 , 384 , 385 , , 386 , 387 , 388 , , 387 , 388 , 387 , 388 , 389 , 387 , 390 , 391 , 387 , 388 , 391 , 387 , 392 , 393 , , 393 , 394 , 395 , 393 , 393 , 393 , 393 , 395 , 396 , 396 , 396 , 397 , 398 , 396 , 399 , 397 , 400 , 400 , 400 , 401 , 402 , 402 , 396 , 399 , 396 , 399 , , 396 , 399 , 403 , 404 , 403 , 403 , 405 , 404 , , 404 , 406 , 407 , 408 , 406 , 407 , 409 , 406 , 407 , 406 , 407 , 409 , 406 , 406 , 407 , , 410 , 410 , 410 , 411 , 410 , 412 , 412 , 410 , 410 , 410 , 410 , 411 , , 410 , 413 , , 413 , 414 , 414 , 413 , 413 , 414 , 415 , 416 , 415 , 415 , 415 , 415 , 415 , 417 , 418 , 419 , , 415 , 420 , , 421 , 420 , 421 , 422 , 420 , 421 , 423 , 420 , 421 , 423 , 424 , 424 , 424 , 424 , 424 , 424 , 424 , 425 , , 424 , 426 , 426 , 427 , 428 , 429 , 429 , , 429 , 430 , 430 , , 430 , 430 , 430 , 430 , 431 , 432 , 433 , 434 , 433 , 435 , 435 , 435 , 436 , 437 , 437 , 432 , 438 , 432 , 438 , 432 , 438 , , 439 , 439 , 440 , 439 , 441 , 442 , 443 , 442 , 442 , 444 , 444 , 439 , 441 , 439 , 441 , , 439 , 441 , 445 , 445 , 445 , 446 , 447 , 448 , 449 , 449 , 447 , 449 , 450 , 445 , 446 , , 445 , 446 , 451 , 451 , 451 , 452 , 453 , 454 , 455 , 455 , 453 , 451 , 452 , 451 , 452 , , 455 , 456 , 457 , 458 , , 458 , 459 , 457 , 460 , , 460 , 461 , 460 , 460 , 460 , 460 , 462 , 463 , 464 , 465 , 463 , 464 , 466 , 463 , 464 , 467 , 467 , 464 , 466 , , 468 , , 469 , 470 , 471 , 471 , 472 , 473 , , 474 , , 474 , 475 , 474 , 474 , 476 , , 476 , 477 , 478 , 476 , 479 , 476 , 480 , 476 , 476 , 476 , 476 , 477 , 477 , 476 , 481 , , 482 , 483 , 482 , 484 , 482 , 485 , , 486 , 487 , 488 , 488 , 489 , 486 , 486 , , 490 , 491 , 492 , 493 , 493 , 490 , , 494 , 495 , , 494 , 496 , 496 , 497 , , 497 , 497 , 497 , 497 , 498 , 499 , 499 , 500 , , 500 , 500
      BMC Genomics
      BioMed Central
      The 3rd International Genomic Medicine Conference (3rd IGMC 2015)
      30 November - 3 December 2015

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          Table of contents

          O1 Regulation of genes by telomere length over long distances

          Jerry W. Shay

          O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy

          Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa

          O3 Integration of metagenomics and metabolomics in gut microbiome research

          Maryam Goudarzi, Albert J. Fornace Jr.

          O4 A unique integrated system to discern pathogenesis of central nervous system tumors

          Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri

          O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis

          Heba Alkhatabi

          O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service

          Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp

          O7 Targeted sequencing panels and their utilization in personalized medicine

          Adel M. Abuzenadah

          O8 International biobanking in the era of precision medicine

          Jim Vaught

          O9 Biobank and biodata for clinical and forensic applications

          Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida

          O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors

          Jaudah Al-Maghrabi

          O11 The CEGMR biobanking unit: achievements, challenges and future plans

          Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad

          O12 Phylomedicine of tumors

          Sudhir Kumar, Sayaka Miura, Karen Gomez

          O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment

          Angel Carracedo, Mahmood Rasool

          O14 From association to causality: translation of GWAS findings for genomic medicine

          Ahmed Rebai

          O15 E-GRASP: an interactive database and web application for efficient analysis of disease-associated genetic information

          Sajjad Karim, Hend F Nour Eldin, Heba Abusamra, Elham M Alhathli, Nada Salem, Mohammed H Al-Qahtani, Sudhir Kumar

          O16 The supercomputer facility “AZIZ” at KAU: utility and future prospects

          Hossam Faheem

          O17 New research into the causes of male infertility

          Ashok Agarwa

          O18 The Klinefelter syndrome: recent progress in pathophysiology and management

          Eberhard Nieschlag, Joachim Wistuba, Oliver S. Damm, Mohd A. Beg, Taha A. Abdel-Meguid, Hisham A. Mosli, Osama S. Bajouh, Adel M. Abuzenadah, Mohammed H. Al-Qahtani

          O19 A new look to reproductive medicine in the era of genomics

          Serdar Coskun

          P1 Wnt signalling receptors expression in Saudi breast cancer patients

          Muhammad Abu-Elmagd, Abdelbaset Buhmeida, Ashraf Dallol, Jaudah Al-Maghrabi, Sahar Hakamy, Wejdan Al-Qahtani, Asia Al-Harbi, Shireen Hussain, Mourad Assidi, Mohammed Al-Qahtani, Adel Abuzenadah

          P2 Analysis of oxidative stress interactome during spermatogenesis: a systems biology approach to reproduction

          Burak Ozkosem, Rick DuBois

          P3 Interleukin-18 gene variants are strongly associated with idiopathic recurrent pregnancy loss.

          Safia S Messaoudi, Maryam T Dandana, Touhami Mahjoub, Wassim Y Almawi

          P4 Effect of environmental factors on gene-gene and gene-environment reactions: model and theoretical study applied to environmental interventions using genotype

          S. Abdalla, M. Nabil Al-Aama

          P5 Genomics and transcriptomic analysis of imatinib resistance in gastrointestinal stromal tumor

          Asmaa Elzawahry, Tsuyoshi Takahashi, Sachiyo Mimaki, Eisaku Furukawa, Rie Nakatsuka, Isao Kurosaka, Takahiko Nishigaki, Hiromi Nakamura, Satoshi Serada, Tetsuji Naka, Seiichi Hirota, Tatsuhiro Shibata, Katsuya Tsuchihara, Toshirou Nishida, Mamoru Kato

          P6 In-Silico analysis of putative HCV epitopes against Pakistani human leukocyte antigen background: an approach towards development of future vaccines for Pakistani population

          Sajid Mehmood, Naeem Mahmood Ashraf, Awais Asif, Muhammad Bilal, Malik Siddique Mehmood, Aadil Hussain

          P7 Inhibition of AChE and BuChE with the natural compounds of Bacopa monerri for the treatment of Alzheimer’s disease: a bioinformatics approach

          Qazi Mohammad Sajid Jamal, Mughees Uddin Siddiqui, Mohammad A. Alzohairy, Mohammad A. Al Karaawi

          P8 Her2 expression in urothelial cell carcinoma of the bladder in Saudi Arabia

          Taoufik Nedjadi, Jaudah Al-Maghrabi, Mourad Assidi, Heba Al-Khattabi, Adel Al-Ammari, Ahmed Al-Sayyad, Abdelbaset Buhmeida, Mohammed Al-Qahtani

          P9 Association of angiotensinogen single nucleotide polymorphisms with Preeclampsia in patients from North Africa

          Hédia Zitouni, Nozha Raguema, Marwa Ben Ali, Wided Malah, Raja Lfalah, Wassim Almawi, Touhami Mahjoub

          P10 Systems biology analysis reveals relations between normal skin, benign nevi and malignant melanoma

          Mohammed Elanbari, Andrey Ptitsyn

          P11 The apoptotic effect of thymoquinone in Jurkat cells

          Sana Mahjoub, Rabeb El Ghali, Bechir Achour, Nidhal Ben Amor, Mourad Assidi, Brahim N'siri, Hamid Morjani

          P12 Sonic hedgehog contributes in bladder cancer invasion in Saudi Arabia

          Taoufik Nedjadi, Adel Al-Ammari, Ahmed Al-Sayyad, Nada Salem, Esam Azhar, Jaudah Al-Maghrabi

          P13 Association of Interleukin 18 gene promoter polymorphisms - 607A/C and -137 G/C with colorectal cancer onset in a sample of Tunisian population

          Vera Chayeb, Maryam Dendena, Hedia Zitouni, Khedija Zouari-Limayem, Touhami Mahjoub

          P14 Pathological expression of interleukin-6, -11, leukemia inhibitory factor and their receptors in tubal gestation with and without tubal cytomegalovirus infection

          Bassem Refaat, Ahmed M Ashshi, Sarah A Batwa

          P15 Phenotypic and genetic profiling of avian pathogenic and human diarrhegenic Escherichia coli in Egypt

          Hazem Ramadan, Amal Awad, Ahmed Ateya

          P16 Cancer-targeting dual gene virotherapy as a promising therapeutic strategy for treatment of hepatocellular carcinoma

          Adel Galal Ahmed El-Shemi, Ahmad Ashshi, Mohammed Basalamah, Youjin Na, Chae-Ok YUN

          P17 Cancer dual gene therapy with oncolytic adenoviruses expressing TRAIL and IL-12 transgenes markedly eradicated human hepatocellular carcinoma both in vitro and in vivo

          Adel Galal Ahmed El-Shemi, Ahmad Ashshi, Mohammed Basalamah, Youjin Na, Chae-Ok Yun

          P18 Therapy with paricalcitol attenuates tumor growth and augments tumoricidal and anti-oncogenic effects of 5-fluorouracil on animal model of colon cancer

          Adel Galal El-Shemi, Bassem Refaat, Osama Kensara, Amr Abdelfattah

          P19 The effects of Rubus idaeus extract on normal human lymphocytes and cancer cell line

          Batol Imran Dheeb, Mohammed M. F. Al-Halbosiy, Rghad Kadhim Al lihabi, Basim Mohammed Khashman

          P20 Etanercept, a TNF-alpha inhibitor, alleviates mechanical hypersensitivity and spontaneous pain in a rat model of chemotherapy-induced neuropathic pain

          Djouhri, Laiche, Chaudhary Adeel, Nedjadi, Taoufik

          P21 Sleeping beauty mutagenesis system identified genes and neuronal transcription factor network involved in pediatric solid tumour (medulloblastoma)

          Hani Al-Afghani, Maria Łastowska, Haya H Al-Balool, Harsh Sheth, Emma Mercer, Jonathan M Coxhead, Chris PF Redfern, Heiko Peters, Alastair D Burt, Mauro Santibanez-Koref, Chris M Bacon, Louis Chesler, Alistair G Rust, David J Adams, Daniel Williamson, Steven C Clifford, Michael S Jackson

          P22 Involvement of interleukin-1 in vitiligo pathogenesis

          Mala Singh, Mohmmad Shoab Mansuri, Shahnawaz D. Jadeja, Hima Patel, Yogesh S. Marfatia, Rasheedunnisa Begum

          P23 Cytogenetics abnormalities in 12,884 referred population for chromosomal analysis and the role of FISH in refining the diagnosis (cytogenetic experience 2004-2013)

          Amal M Mohamed, Alaa K Kamel, Nivin A Helmy, Sayda A Hammad, Hesham F Kayed, Marwa I Shehab, Assad El Gerzawy, Maha M. Ead, Ola M Ead, Mona Mekkawy, Innas Mazen, Mona El-Ruby

          P24 Analysis of binding properties of angiotensin-converting enzyme 2 through in silico method

          S. M. A. Shahid, Qazi Mohammad Sajid Jamal, J. M. Arif, Mohtashim Lohani

          P25 Relationship of genetics markers cis and trans to the β-S globin gene with fetal hemoglobin expression in Tunisian sickle cell patients

          Moumni Imen, Chaouch Leila, Ouragini Houyem, Douzi Kais, Chaouachi Dorra Mellouli Fethi, Bejaoui Mohamed, Abbes Salem

          P26 Analysis of estrogen receptor alpha gene polymorphisms in breast cancer: link to genetic predisposition in Sudanese women

          Areeg Faggad, Amanuel T Gebreslasie, Hani Y Zaki, Badreldin E Abdalla

          P27 KCNQI gene polymorphism and its association with CVD and T2DM in the Saudi population

          Maha S AlShammari, Rhaya Al-Ali, Nader Al-Balawi , Mansour Al-Enazi, Ali Al-Muraikhi, Fadi Busaleh, Ali Al-Sahwan, Francis Borgio, Abdulazeez Sayyed, Amein Al-Ali, Sadananda Acharya

          P28 Clinical, neuroimaging and cytogenetic study of a patient with microcephaly capillary malformation syndrome

          Maha S. Zaki, Hala T. El-Bassyouni, Marwa I. Shehab

          P29 Altered expression of CD200R1 on dendritic cells of patients with inflammatory bowel diseases: in silico investigations and clinical evaluations

          Mohammed F. Elshal, Kaleemuddin M., Alia M. Aldahlawi, Omar Saadah,

          J. Philip McCoy

          P30 Development of real time PCR diagnostic protocol specific for the Saudi Arabian H1N1 viral strains

          Adel E El-Tarras, Nabil S Awad, Abdulla A Alharthi, Mohamed M M Ibrahim

          P31 Identification of novel genetic variations affecting Osteoarthritis patients

          Haneen S Alsehli, Ashraf Dallol, Abdullah M Gari, Mohammed M Abbas, Roaa A Kadam, Mazen M. Gari, Mohmmed H Alkaff, Adel M Abuzenadah, Mamdooh A Gari

          P32 An integrated database of GWAS SNVs and their evolutionary properties

          Heba Abusamra, Sajjad Karim, Hend F Nour eldin, Elham M Alhathli, Nada Salem, Sudhir Kumar, Mohammed H Al-Qahtani

          P33 Familial hypercholesterolemia in Saudi Arabia: prime time for a national registry and genetic analysis

          Fatima A. Moradi, Omran M. Rashidi, Zuhier A. Awan

          P34 Comparative genomics and network-based analyses of early hepatocellular carcinoma

          Ibrahim Hamza Kaya, Olfat Al-Harazi, Dilek Colak

          P35 A TALEN-based oncolytic viral vector approach to knock out ABCB1 gene mediated chemoresistance in cancer stem cells

          Nabila A Alkousi, Takis Athanasopoulos

          P36 Cartilage differentiation and gene expression of synovial fluid mesenchymal stem cells derived from osteoarthritis patients

          Afnan O Bahmaid, Etimad A Alhwait, Mamdooh A Gari, Haneen S Alsehli, Mohammed M Abbas, Mohammed H Alkaf, Roaa Kadam, Ashraf Dallol, Gauthaman Kalamegam

          P37 E-GRASP: Adding an evolutionary component to the genome-wide repository of associations (GRASP) resource

          Hend F Nour Eldin, Sajjad Karim, Heba Abusamra, Elham Alhathli, Nada Salem, Mohammed H Al-Qahtani, Sudhir Kumar

          P38 Screening of AGL gene mutation in Saudi family with glycogen storage disease Type III

          Salma N Alsayed, Fawziah H Aljohani, Samaher M Habeeb, Rawan A Almashali, Sulman Basit, Samia M Ahmed

          P39 High throughput proteomic data suggest modulation of cAMP dependent protein kinase A and mitochondrial function in infertile patients with varicocele

          Rakesh Sharma, Ashok Agarwal, Damayanthi Durairajanayagam, Luna Samanta, Muhammad Abu-Elmagd, Adel M. Abuzenadah, Edmund S. Sabanegh, Mourad Assidi, Mohammed Al-Qahtani

          P40 Significant protein profile alterations in men with primary and secondary infertility

          Ashok Agarwal, Rakesh Sharma, Luna Samanta, Damayanthi Durairajanayagam, Mourad Assidi, Muhammad Abu-Elmagd, Mohammed Al-Qahtani, Adel M. Abuzenadah, Edmund S. Sabanegh

          P41 Spermatozoa maturation in infertile patients involves compromised expression of heat shock proteins

          Luna Samanta, Ashok Agarwal, Rakesh Sharma, Zhihong Cui, Mourad Assidi, Adel M. Abuzenadah, Muhammad Abu-Elmagd, Mohammed Al-Qahtani

          P42 Array comparative genomic hybridization approach to search genomic answers for spontaneous recurrent abortion in Saudi Arabia

          Alaa A Alboogmi, Nuha A Alansari, Maha M Al-Quaiti, Fai T Ashgan, Afnan Bandah, Hasan S Jamal, Abdullraheem Rozi , Zeenat Mirza, Adel M Abuzenadah, Sajjad Karim, Mohammed H Al-Qahtani

          P43 Global gene expression profiling of Saudi kidney cancer patients

          Sajjad Karim, Hans-Juergen Schulten, Ahmad J Al Sayyad, Hasan MA Farsi, Jaudah A Al-Maghrabi, Zeenat Mirza, Reem Alotibi, Alaa Al-Ahmadi, Nuha A Alansari, Alaa A Albogmi, Maha M Al-Quaiti, Fai T Ashgan, Afnan Bandah, Mohammed H Al-Qahtani

          P44 Downregulated StAR gene and male reproductive dysfunction caused by nifedipine and ethosuximide

          Rasha A Ebiya, Samia M Darwish, Metwally M. Montaser

          P45 Clustering based gene expression feature selection method: A computational approach to enrich the classifier efficiency of differentially expressed genes

          Heba Abusamra, Vladimir B. Bajic

          P46 Prognostic significance of Osteopontin expression profile in colorectal carcinoma

          Jaudah Al-Maghrabi, Wafaey Gomaa, Mehenaz Hanbazazh, Mahmoud Al-Ahwal, Asia Al-Harbi, Wejdan Al-Qahtani, Saher Hakamy, Ghali Baba, Abdelbaset Buhmeida, Mohammed Al-Qahtani

          P47 High Glypican-3 expression pattern predicts longer disease-specific survival in colorectal carcinoma

          Jaudah Al-Maghrabi, Abdullah Al-Harbi, Mahmoud Al-Ahwal, Asia Al-Harbi, Wejdan Al-Qahtani, Sahar Hakamy, Ghalia Baba, Abdelbaset Buhmeida, Mohammed Al-Qahtani

          P48 An evolutionary re-assessment of GWAS single nucleotide variants implicated in the Cholesterol traits

          Elham M Alhathli, Sajjad Karim, Nada Salem, Hend Nour Eldin, Heba Abusamra, Sudhir Kumar, Mohammed H Al-Qahtani

          P49 Derivation and characterization of human Wharton’s jelly stem cells (hWJSCs) in vitro for future therapeutic applications

          Aisha A Alyamani, Gauthaman Kalamegam, Etimad A Alhwait, Mamdooh A Gari, Mohammed M Abbas, Mohammed H Alkaf, Haneen S Alsehli, Roaa A Kadam, Mohammed Al-Qahtani

          P50 Attitudes of healthcare students toward biomedical research in the post-genomic era

          Rawan Gadi, Abdelbaset Buhmeida, Mourad Assidi , Adeel Chaudhary, Leena Merdad

          P51 Evaluation of the immunomodulatory effects of thymoquinone on human bone marrow mesenchymal stem cells (BM-MSCs) from osteoarthritic patients

          Saadiah M Alfakeeh, Etimad A Alhwait, Mamdooh A Gari, Mohammed M Abbas, Mohammed H Alkaf, Haneen S Alsehli, Roaa Kadam, Gauthaman Kalamegam

          P52 Implication of IL-10 and IL-28 polymorphism with successful anti-HCV therapy and viral clearance

          Rubi Ghazala, Shilu Mathew, M.Haroon Hamed, Mourad Assidi, Mohammed Al-Qahtani, Ishtiaq Qadri

          P53 Selection of flavonoids against obesity protein (FTO) using in silico and in vitro approaches

          Shilu Mathew, Lobna Mira, Manal Shaabad, Shireen Hussain, Mourad Assidi, Muhammad Abu-Elmagd, Mohammed Al-Qahtani

          P54 Computational selection and in vitro validation of flavonoids as new antidepressant agents

          Shilu Mathew, Manal Shaabad, Lobna Mira, Shireen Hussain, Mourad Assidi, Muhammad Abu-Elmagd, Mohammed Al-Qahtani

          P55 In Silico prediction and prioritization of aging candidate genes associated with

          progressive telomere shortening

          Ahmed Rebai, Mourad Assidi, Abdelbaset Buhmeida, Muhammad Abu-Elmagd, Ashraf Dallol, Jerry W Shay

          P56 Identification of new cancer testis antigen genes in diverse types of malignant human tumour cells

          Mikhlid H Almutairi

          P57 More comprehensive forensic genetic marker analyses for accurate human remains identification using massively parallel sequencing (MPS)

          Angie Ambers, Jennifer Churchill, Jonathan King, Monika Stoljarova, Harrell Gill-King, Mourad Assidi, Muhammad Abu-Elmagd, Abdelbaset Buhmeida, Muhammad Al-Qatani, Bruce Budowle

          P58 Flow cytometry approach towards treatment men infertility in Saudi Arabia

          Muhammad Abu-Elmagd, Farid Ahmed, Ashraf Dallol, Mourad Assidi, Taha Abo Almagd, Sahar Hakamy, Ashok Agarwal, Muhammad Al-Qahtani, Adel Abuzenadah

          P59 Tissue microarray based validation of CyclinD1 expression in renal cell carcinoma of Saudi kidney patients

          Sajjad Karim, Hans-Juergen Schulten, Ahmad J Al Sayyad, Hasan MA Farsi, Jaudah A Al-Maghrabi, Abdelbaset Buhmaida, Zeenat Mirza, Reem Alotibi, Alaa Al-Ahmadi, Nuha A Alansari, Alaa A Albogmi, Maha M Al-Quaiti, Fai T Ashgan, Afnan Bandah, Mohammed H Al-Qahtani

          P60 Assessment of gold nanoparticles in molecular diagnostics and DNA damage studies

          Rukhsana Satar, Mahmood Rasool, Waseem Ahmad, Nazia Nazam, Mohamad I Lone, Muhammad I Naseer, Mohammad S Jamal, Syed K Zaidi, Peter N Pushparaj, Mohammad A Jafri, Shakeel A Ansari, Mohammed H Alqahtani

          P61 Surfing the biospecimen management and processing workflow at CEGMR Biobank

          Hanan Bashier, Abrar Al Qahtani, Shilu Mathew, Amal M. Nour, Heba Alkhatabi, Adel M. Abu Zenadah, Abdelbaset Buhmeida, Mourad Assidi, Muhammed Al Qahtani

          P62 Autism Spectrum Disorder: knowledge, attitude and awareness in Jeddah, Kingdom of Saudi Arabia

          Muhammad Faheem, Shilu Mathew, Shiny Mathew, Peter Natesan Pushparaj, Mohammad H. Al-Qahtani

          P63 Simultaneous genetic screening of the coagulation pathway genes using the Thromboscan targeted sequencing panel

          Hani A. Alhadrami, Ashraf Dallol, Adel Abuzenadah

          P64 Genome wide array comparative genomic hybridization analysis in patients with syndromic congenital heart defects

          Ibtessam R. Hussein, Adeel G. Chaudhary, Rima S Bader, Randa Bassiouni, Maha Alquaiti, Fai Ashgan, Hans Schulten, Mohamed Nabil Alama, Mohammad H. Al Qahtani

          P65 Toxocogenetic evaluation of 1, 2-Dichloroethane in bone marrow, blood and cells of immune system using conventional, molecular and flowcytometric approaches

          Mohammad I Lone, Nazia Nizam, Waseem Ahmad, Mohammad A Jafri, Mahmood Rasool, Shakeel A Ansari, Muhammed H Al-Qahtani

          P66 Molecular cytogenetic diagnosis of sexual development disorders in newborn: A case of ambiguous genitalia

          Eradah Alshihri, Muhammad Abu-Elmagd, Lina Alharbi, Mourad Assidi, Mohammed Al-Qahtani

          P67 Identification of disease specific gene expression clusters and pathways in hepatocellular carcinoma using In Silico methodologies

          Shilu Mathew, Peter Pushparaj Natesan, Muhammed Al Qahtani

          P68 Human Wharton’s Jelly stem cell conditioned medium inhibits primary ovarian cancer cells in vitro: Identification of probable targets and mechanisms using systems biology

          Gauthaman Kalamegam, Peter Natesan Pushparaj, Fazal Khan, Roaa Kadam, Farid Ahmed, Mourad Assidi, Khalid Hussain Wali Sait, Nisreen Anfinan, Mohammed Al Qahtani

          P69 Mutation spectrum of ASPM (Abnormal Spindle-like, Microcephaly-associated) gene in Saudi Arabian population

          Muhammad I Naseer, Adeel G Chaudhary, Mohammad S Jamal, Shilu Mathew, Lobna S Mira, Peter N Pushparaj, Shakeel A Ansari, Mahmood Rasool, Mohammed H AlQahtani

          P70 Identification and characterization of novel genes and mutations of primary microcephaly in Saudi Arabian population

          Muhammad I Naseer, Adeel G Chaudhary, Shilu Mathew, Lobna S Mira, Mohammad S Jamal, Sameera Sogaty, Randa I Bassiouni, Mahmood Rasool, Mohammed H AlQahtani

          P71 Molecular genetic analysis of hereditary nonpolyposis colorectal cancer (Lynch Syndrome) in Saudi Arabian population

          Mahmood Rasool, Shakeel A Ansari, Mohammad S Jamal, Peter N Pushparaj, Abdulrahman MS Sibiani, Waseem Ahmad, Abdelbaset Buhmeida, Mohammad A Jafri, Mohiuddin K Warsi, Muhammad I Naseer, Mohammed H Al-Qahtani

          P72 Function predication of hypothetical proteins from genome database of chlamydia trachomatis

          Rubi, Kundan Kumar, Ahmad AT Naqvi, Faizan Ahmad, Md I Hassan, Mohammad S Jamal, Mahmood Rasool, Mohammed H AlQahtani

          P73 Transcription factors as novel molecular targets for skin cancer

          Ashraf Ali, Jummanah Jarullah, Mahmood Rasool, Abdelbasit Buhmeida, Shahida Khan, Ghufrana Abdussami, Maryam Mahfooz, Mohammad A Kamal, Ghazi A Damanhouri, Mohammad S Jamal

          P74 An In Silico analysis of Plumbagin binding to apoptosis executioner: Caspase-3 and Caspase-7

          Bushra Jarullah, Jummanah Jarullah, Mohammad SS Jarullah, Ashraf Ali, Mahmood Rasool, Mohammad S Jamal

          P75 Single cell genomics applications for preimplantation genetic screening optimization: Comparative analysis of whole genome amplification technologies

          Mourad Assidi, Muhammad Abu-Elmagd, Osama Bajouh, Peter Natesan Pushparaj, Mohammed Al-Qahtani, Adel Abuzenadah

          P76 ZFP36 regulates miRs-34a in anti-IgM triggered immature B cells

          Mohammad S Jamal, Jummanah Jarullah, Abdulah EA Mathkoor, Hashim MA Alsalmi, Anas MM Oun, Ghazi A Damanhauri, Mahmood Rasool, Mohammed H AlQahtani

          P77 Identification of a novel mutation in the STAMBP gene in a family with microcephaly-capillary malformation syndrome

          Muhammad I. Naseer, Mahmood Rasool, Sameera Sogaty, Adeel G. Chudhary, Yousif A. Abutalib, Daniele Merico, Susan Walker, Christian R. Marshall, Mehdi Zarrei, Stephen W. Scherer, Mohammad H. Al-Qahtani

          P78 Copy number variations in Saudi patients with intellectual disability and epilepsy

          Muhammad I. Naseer, Muhammad Faheem, Adeel G. Chaudhary, Mahmood Rasool, Gauthaman Kalamegam, Fai Talal Ashgan, Mourad Assidi, Farid Ahmed, Syed Kashif Zaidi, Mohammed M. Jan, Mohammad H. Al-Qahtani

          P79 Prognostic significance of CD44 expression profile in colorectal carcinoma

          Maryam Al-Zahrani, Sahira Lary, Sahar Hakamy, Ashraf Dallol, Mahmoud Al-Ahwal, Jaudah Al-Maghrabi, Emmanuel Dermitzakis, Adel Abuzenadah, Abdelbaset Buhmeida, Mohammed Al-Qahtani

          P80 Association of the endothelial nitric oxide synthase (eNOS) gene G894T polymorphism with hypertension risk and complications

          Abeer A Al-refai, Mona Saleh, Rehab I Yassien, Mahmmoud Kamel, Rabab M Habeb

          P81 SNPs array to screen genetic variation among diabetic patients

          Najlaa Filimban, Ashraf Dallol, Nadia Ghannam, Mohammed Al-Qahtani, Adel Mohammed Abuzenadah

          P82 Detection and genotyping of Helicobacter pylori among gastric cancer patients from Saudi Arabian population

          Fehmida Bibi, Sana Akhtar, Esam I. Azhar, Muhammad Yasir, Muhammad I. Nasser, Asif A. Jiman-Fatani, Ali Sawan

          P83 Antimicrobial drug resistance and molecular detection of susceptibility to Fluoroquinolones among clinical isolates of Salmonella species from Jeddah-Saudi Arabia

          Ruaa A Lahzah, Asho Ali

          P84 Identification of the toxic and virulence nature of MAP1138c protein of Mycobacterium avium subsp. paratuberculosis

          Syed A Hassan, Seyed E Hasnain, Iftikhar A Tayubi, Hamza A Abujabal, Alaa O Magrabi

          P85 In vitro and in silico evaluation of miR137 in human breast cancer

          Fazal Khan, Gauthaman Kalamegam, Peter Natesan Pushparaj, Adel Abuzenada, Taha Abduallah Kumosani, Elie Barbour, Mohammed Al-Qahtani

          P86 Auruka gene is over-expressed in Saudi breast cancer

          Manal Shabaad, Shilu Mathew, Ashraf Dallol, Adnan Merdad, Abdelbaset Buhmeida, Mohammed Al-Qahtani

          P87 The potential of immunogenomics in personalized healthcare

          Mourad Assidi, Muhammad Abu-Elmagd, Kalamegam Gauthaman, Mamdooh Gari, Adeel Chaudhary, Adel Abuzenadah, Peter Natesan Pushparaj, Mohammed Al-Qahtani

          P88 In Silico physiochemical and structural characterization of a putative ORF MAP0591 and its implication in the pathogenesis of Mycobacterium paratuberculosis in ruminants and humans

          Syed A Hassan, Iftikhar A Tayubi, Hani MA Aljahdali

          P89 Effects of heat shock on human bone marrow mesenchymal stem cells (BM-MSCs): Implications in regenerative medicine

          Reham Al Nono, Mamdooh Gari, Haneen Alsehli, Farid Ahmed, Mohammed Abbas, Gauthaman Kalamegam, Mohammed Al-Qahtani

          P90 In Silico analyses of the molecular targets of Resveratrol unravels its importance in mast cell mediated allergic responses

          Shilu Mathew, Fazal Khan, Mahmood Rasool, Mohammed Sarwar Jamal, Muhammad Imran Naseer, Zeenat Mirza, Sajjad Karim, Shakeel Ansari, Mourad Assidi, Gauthaman Kalamegam, Mamdooh Gari, Adeel Chaudhary, Adel Abuzenadah, Peter Natesan Pushparaj, Mohammed Al-Qahtani

          P91 Effects of environmental particulate matter on bone-marrow mesenchymal stem cells

          Muhammad Abu-Elmagd, Gauthaman Kalamegam, Roaa Kadam, Mansour A Alghamdi, Magdy Shamy, Max Costa, Mamdouh I Khoder, Mourad Assidi, Peter Natesan Pushparaj, Mamdooh Gari, Mohammed Al-Qahtani

          P92 Distinctive charge clusters in human virus proteomes

          Najla Kharrat, Sabrine Belmabrouk, Rania Abdelhedi, Riadh Benmarzoug, Mourad Assidi, Mohammed H. Al Qahtani, Ahmed Rebai

          P93 In vitro experimental model and approach in identification of new biomarkers of inflammatory forms of arthritis

          Ghazi Dhamanhouri, Peter Natesan Pushparaj, Abdelwahab Noorwali, Mohammad Khalid Alwasiyah, Afnan Bahamaid, Saadiah Alfakeeh, Aisha Alyamani, Haneen Alsehli, Mohammed Abbas, Mamdooh Gari, Ali Mobasheri, Gauthaman Kalamegam, Mohammed Al-Qahtani

          P94 Molecular docking of GABA A receptor subunit γ-2 with novel anti-epileptic compounds

          Muhammad Faheem, Shilu Mathew, Peter Natesan Pushparaj, Mohammad H. Al-Qahtani

          P95 Breast cancer knowledge, awareness, and practices among Saudi females residing in Jeddah

          Shilu Mathew, Muhammad Faheem, Shiny Mathew, Peter Natesan Pushparaj, Mohammad H. Al-Qahtani

          P96 Anti-inflammatory role of Sesamin by Attenuation of Iba1/TNF-α/ICAM-1/iNOS signaling in Diabetic Retinopathy

          Mohammad Sarwar Jamal, Syed Kashif Zaidi, Raziuddin Khan, Kanchan Bhatia, Mohammed H. Al-Qahtani, Saif Ahmad

          P97 Identification of drug lead molecule against vp35 protein of Ebola virus: An In-Silico approach

          Iftikhar AslamTayubi, Manish Tripathi, Syed Asif Hassan, Rahul Shrivastava

          P98 An approach to personalized medicine from SNP-calling through disease analysis using whole exome-sequencing of three sub-continental populations

          Iftikhar A Tayubi, Syed Hassan, Hamza A.S Abujabal

          P99 Low versus high frequency of Glucose –6 – Phosphate Dehydrogenase (G6PD) deficiency in urban against tribal population of Gujarat – A signal to natural selection

          Ishani Shah, Bushra Jarullah, Mohammad S Jamal, Jummanah Jarullah

          P100 Spontaneous preterm birth and single nucleotide gene polymorphisms: a recent update

          Ishfaq A Sheikh, Ejaz Ahmad, Mohammad S Jamal, Mohd Rehan, Muhammad Abu-Elmagd, Iftikhar A Tayubi, Samera F AlBasri, Osama S Bajouh, Rola F Turki, Adel M Abuzenadah, Ghazi A Damanhouri, Mohd A Beg, Mohammed Al-Qahtani

          P101 Prevalence of congenital heart diseases among Down syndrome cases in Saudi Arabia: role of molecular genetics in the pathogenesis

          Sahar AF Hammoudah, Khalid M AlHarbi, Lama M El-Attar, Ahmed MZ Darwish

          P102 Combinatorial efficacy of specific pathway inhibitors in breast cancer cells

          Sara M Ibrahim, Ashraf Dallol , Hani Choudhry, Adel Abuzenadah, Jalaludden Awlia, Adeel Chaudhary, Farid Ahmed, Mohammed Al-Qahtani

          P103 MiR-143 and miR-145 cluster as potential replacement medicine for the treatment of cancer

          Mohammad A Jafri, Muhammad Abu-Elmagd, Mourad Assidi, Mohammed Al-Qahtani

          P104 Metagenomic profile of gut microbiota during pregnancy in Saudi population

          Imran khan, Muhammad Yasir, Esam I. Azhar, Sameera Al-basri, Elie Barbour, Taha Kumosani

          P105 Exploration of anticancer targets of selected metabolites of Phoenix dactylifera L. using systems biological approaches

          Fazal Khan, Gauthaman Kalamegam, Peter Natesan Pushparaj, Adel Abuzenada, Taha Abduallah Kumosani, Elie Barbour

          P106 CD226 and CD40 gene polymorphism in susceptibility to Juvenile rheumatoid arthritis in Egyptian patients

          Heba M. EL Sayed, Eman A. Hafez

          P107 Paediatric exome sequencing in autism spectrum disorder ascertained in Saudi families

          Hans-Juergen Schulten, Aisha Hassan Elaimi, Ibtessam R Hussein, Randa Ibrahim Bassiouni, Mohammad Khalid Alwasiyah, Richard F Wintle, Adeel Chaudhary, Stephen W Scherer, Mohammed Al-Qahtani

          P108 Crystal structure of the complex formed between Phospholipase A 2 and the central core hydrophobic fragment of Alzheimer’s β- amyloid peptide: a reductionist approach

          Zeenat Mirza, Vikram Gopalakrishna Pillai, Sajjad Karim, Sujata Sharma, Punit Kaur, Alagiri Srinivasan, Tej P Singh, Mohammed Al-Qahtani

          P109 Differential expression profiling between meningiomas from female and male patients

          Reem Alotibi, Alaa Al-Ahmadi, Fatima Al-Adwani, Deema Hussein, Sajjad Karim, Mona Al-Sharif, Awatif Jamal, Fahad Al-Ghamdi, Jaudah Al-Maghrabi, Saleh S Baeesa, Mohammed Bangash, Adeel Chaudhary, Hans-Juergen Schulten, Mohammed Al-Qahtani

          P110 Neurospheres as models of early brain development and therapeutics

          Muhammad Faheem, Peter Natesan Pushparaj, Shilu Mathew, Taha Abdullah Kumosani, Gauthaman Kalamegam, Mohammed Al-Qahtani

          P111 Identification of a recurrent causative missense mutation p.(W577C) at the LDLR exon 12 in familial hypercholesterolemia affected Saudi families

          Faisal A Al-Allaf, Zainularifeen Abduljaleel, Abdullah Alashwal, Mohiuddin M. Taher, Abdellatif Bouazzaoui, Halah Abalkhail, Faisal A. Ba-Hammam, Mohammad Athar

          P112 Epithelial ovarian carcinoma (EOC): Systems oncological approach to identify diagnostic, prognostic and therapeutic biomarkers

          Gauthaman Kalamegam, Peter Natesan Pushparaj, Muhammad Abu-Elmagd, Farid Ahmed Khalid HussainWali Sait, Nisreen Anfinan, Mamdooh Gari, Adeel Chaudhary, Adel Abuzenadah, Mourad Assidi, Mohammed Al-Qahtani

          P113 Crohn’s disease phenotype in northern Tunisian population

          Naira Ben Mami, Yosr Z Haffani, Mouna Medhioub, Lamine Hamzaoui, Ameur Cherif, Msadok Azouz

          P114 Establishment of In Silico approaches to decipher the potential toxicity and mechanism of action of drug candidates and environmental agents

          Gauthaman Kalamegam, Fazal Khan, Shilu Mathew, Mohammed Imran Nasser, Mahmood Rasool, Farid Ahmed, Peter Natesan Pushparaj, Mohammed Al-Qahtani

          P115 1q Gain predicts poor prognosis marker for young breast cancer patients

          Shereen A Turkistany, Lina M Al-harbi, Ashraf Dallol, Jamal Sabir, Adeel Chaudhary, Adel Abuzenadah

          P116 Disorders of sex chromosomes in a diagnostic genomic medicine unit in Saudi Arabia: Prevalence, diagnosis and future guidelines

          Basmah Al-Madoudi, Bayan Al-Aslani, Khulud Al-Harbi, Rwan Al-Jahdali, Hanadi Qudaih, Emad Al Hamzy, Mourad Assidi, Mohammed Al Qahtani

          P117 Combination of WYE354 and Sunitinib demonstrate synergistic inhibition of acute myeloid leukemia in vitro

          Asad M Ilyas, Youssri Ahmed, Mamdooh Gari, Farid Ahmed, Mohammed Alqahtani

          P118 Integrated use of evolutionary information in GWAS reveals important SNPs in Asthma

          Nada Salem, Sajjad Karim, Elham M Alhathli, Heba Abusamra, Hend F Nour Eldin, Mohammed H Al-Qahtani, Sudhir Kumar

          P119 Assessment of BRAF, IDH1, IDH2, and EGFR mutations in a series of primary brain tumors

          Fatima Al-Adwani, Deema Hussein, Mona Al-Sharif, Awatif Jamal, Fahad Al-Ghamdi, Jaudah Al-Maghrabi, Saleh S Baeesa, Mohammed Bangash, Adeel Chaudhary, Mohammed Al-Qahtani, Hans-Juergen Schulten

          P120 Expression profiles distinguish oligodendrogliomas from glioblastoma multiformes with or without oligodendroglioma component

          Alaa Alamandi, Reem Alotibi, Deema Hussein, Sajjad Karim, Jaudah Al-Maghrabi, Fahad Al-Ghamdi, Awatif Jamal, Saleh S Baeesa, Mohammed Bangash, Adeel Chaudhary, Hans-Juergen Schulten, Mohammed Al-Qahtani

          P121 Hierarchical clustering in thyroid goiters and hyperplastic lesions

          Ohoud Subhi, Nadia Bagatian, Sajjad Karim, Adel Al-Johari, Osman Abdel Al-Hamour, Hosam Al-Aradati, Abdulmonem Al-Mutawa, Faisal Al-Mashat, Jaudah Al-Maghrabi, Hans-Juergen Schulten, Mohammad Al-Qahtani

          P122 Differential expression analysis in thyroiditis and papillary thyroid carcinomas with or without coexisting thyroiditis

          Nadia Bagatian, Ohoud Subhi, Sajjad Karim, Adel Al-Johari, Osman Abdel Al-Hamour, Abdulmonem Al-Mutawa, Hosam Al-Aradati, Faisal Al-Mashat, Mohammad Al-Qahtani, Hans-Juergen Schulten, Jaudah Al-Maghrabi

          P123 Metagenomic analysis of waste water microbiome in Sausdi Arabia

          Muhammad W shah, Muhammad Yasir, Esam I Azhar, Saad Al-Masoodi

          P124 Molecular characterization of Helicobacter pylori from faecal samples of Tunisian patients with gastric cancer

          Yosr Z Haffani, Msadok Azouz, Emna Khamla, Chaima Jlassi, Ahmed S. Masmoudi, Ameur Cherif, Lassaad Belbahri

          P125 Diagnostic application of the oncoscan © panel for the identification of hereditary cancer syndrome

          Shadi Al-Khayyat, Roba Attas, Atlal Abu-Sanad, Mohammed Abuzinadah, Adnan MerdadAshraf Dallol, Adeel Chaudhary, Mohammed Al-Qahtani, Adel Abuzenadah

          P126 Characterization of clinical and neurocognitive features in a family with a novel OGT gene missense mutation c. 1193G > A/ (p. Ala319Thr)

          Habib Bouazzi, Carlos Trujillo, Mohammad Khalid Alwasiyah, Mohammed Al-Qahtani

          P127 Case report: a rare homozygous deletion mutation of TMEM70 gene associated with 3-Methylglutaconic Aciduria and cataract in a Saudi patient

          Maha Alotaibi, Rami Nassir

          P128 Isolation and purification of antimicrobial milk proteins

          Ishfaq A Sheikh, Mohammad A Kamal, Essam H Jiffri, Ghulam M Ashraf, Mohd A Beg

          P129 Integrated analysis reveals association of ATP8B1 gene with colorectal cancer

          Mohammad A Aziz, Rizwan Ali, Mahmood Rasool, Mohammad S Jamal, Nusaibah samman, Ghufrana Abdussami, Sathish Periyasamy, Mohiuddin K Warsi, Mohammed Aldress, Majed Al Otaibi, Zeyad Al Yousef, Mohamed Boudjelal, Abdelbasit Buhmeida, Mohammed H Al-Qahtani, Ibrahim AlAbdulkarim

          P130 Implication of IL-10 and IL-28 polymorphism with successful anti-HCV therapy and viral clearance

          Rubi Ghazala, Shilu Mathew, M. Haroon Hamed, Mourad Assidi, Mohammed Al-Qahtani, Ishtiaq Qadri

          P131 Interactions of endocrine disruptor di-(2-ethylhexyl) phthalate (DEHP) and its metabolite mono-2-ethylhexyl phthalate (MEHP) with progesterone receptor

          Ishfaq A Sheikh, Muhammad Abu-Elmagd, Rola F Turki, Ghazi A Damanhouri, Mohd A. Beg

          P132 Association of HCV nucleotide polymorphism in the development of hepatocellular carcinoma

          Mohd Suhail, Abid Qureshi, Adil Jamal, Peter Natesan Pushparaj, Mohammad Al-Qahtani, Ishtiaq Qadri

          P133 Gene expression profiling by DNA microarrays in colon cancer treated with chelidonine alkaloid

          Mahmoud Z El-Readi, Safaa Y Eid, Michael Wink

          P134 Successful in vitro fertilization after eight failed trials

          Ahmed M. Isa, Lulu Alnuaim, Johara Almutawa, Basim Abu-Rafae, Saleh Alasiri, Saleh Binsaleh

          P135 Genetic sensitivity analysis using SCGE, cell cycle and mitochondrial membrane potential in OPs stressed leukocytes in Rattus norvegicus through flow cytometric input

          Nazia Nazam, Mohamad I Lone, Waseem Ahmad, Shakeel A Ansari, Mohamed H Alqahtani

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          hirokawa@m.u-tokyo.ac.jp
          af294@georgetown.edu
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          Conference
          BMC Genomics
          BMC Genomics
          BMC Genomics
          BioMed Central (London )
          1471-2164
          20 July 2016
          20 July 2016
          2016
          : 17
          Issue : Suppl 6 Issue sponsor : Publication of this supplement was funded by the Centre of Excellence in Genomic Medicine Research. The Supplement Editor declares that they have no competing interests.
          : 487
          Affiliations
          [1 ]University of Texas Southwestern Medical Center, Dallas, TX USA
          [2 ]Department of Cell Biology and Anatomy, Graduate School of Medicine, the University of Tokyo, Tokyo, 113-0033 Japan
          [3 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, 21589 Saudi Arabia
          [4 ]Department of Biochemistry and Molecular & Cellular Biology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC USA
          [5 ]Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC USA
          [6 ]Department of Radiation Medicine, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC USA
          [7 ]Center of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [8 ]King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, Saudi Arabia
          [9 ]Centre of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [10 ]Sheffield Diagnostic Genetic Service, Sheffield Children’s NHS Foundation Trust, Western Bank, Sheffield, UK
          [11 ]Center of Innovations in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [12 ]President, ISBER, Editor-in-Chief, Biopreservation & Biobanking, ᅟ, USA
          [13 ]Institute of Applied Genetics, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, Fort Worth, TX 76107 USA
          [14 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [15 ]Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [16 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [17 ]Department of Dental Public Health, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia
          [18 ]Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA 19122 USA
          [19 ]Genomic Medicine Group- Galician Foundation of Genomic Medicine (SERGAS), CIBERER, University of Santiago de Compostela, Santiago de Compostela, Spain
          [20 ]Center of Excellence in Genomic Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [21 ]Laboratory of Molecular and Cellular Screening Processes (Bioinformatics Group), Centre of Biotechnology of Sfax, P.O. Box “1177”, Sfax, Tunisia
          [22 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, PO Box 80216, Jeddah, 21589 Saudi Arabia
          [23 ]Institute for Genomics and Evolutionary Medicine, Temple University (SERC 602A), Philadelphia, PA 19122 USA
          [24 ]Fujitsu Technology Solutions International, ᅟ, ᅟ
          [25 ]Case Western Reserve University, School of Medicine and Lerner College of Medicine, Cleveland Clinic Foundation, Cleveland, Ohio USA
          [26 ]American Center for Reproductive Medicine, Andrology Center, Cleveland, Ohio USA
          [27 ]Center for Reproductive Medicine and Andrology, University of Münster, Münster, Germany
          [28 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [29 ]Department of Urology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [30 ]Department of Obstetrics and Gynecology, King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia
          [31 ]KACST Technology Innovation Center in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [32 ]Assisted Reproductive Technology Laboratory, Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia
          [33 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [34 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [35 ]Department of Pathology, Faculty of medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [36 ]Biodesign Institute, Arizona State University, Tempe, AZ 85281 USA
          [37 ]Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287 USA
          [38 ]Forensic Biology Department, College of Forensic Sciences, Naif Arab University for Security Sciences, Riyadh, Kingdom of Saudi Arabia
          [39 ]College of Pharmacy of Monastir, Monastir, Tunisia
          [40 ]Department of Medical Biochemistry, Arabian Gulf University, Manama, Bahrain
          [41 ]Department of Physics, Faculty of Science, King Abdulaziz University Jeddah, P.O. Box 80203, Jeddah, 21589 Saudi Arabia
          [42 ]Internal Medicine and Cardiology, King Abdulaziz University Medical School, Jeddah, Saudi Arabia
          [43 ]Department of Bioinformatics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuuoo-ku, Tokyo, 104-0045 Japan
          [44 ]Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, 2-2 E2, Yamadaoka, Suita City, Osaka 565-0871 Japan
          [45 ]Division of Translational Research, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577 Japan
          [46 ]Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuuoo-ku, Tokyo, 104-0045 Japan
          [47 ]Laboratory for Immune Signal, National Institute of Biomedical Innovation, 7-6-8 Saito-Asagi, Ibaraki City, Osaka 567-0085 Japan
          [48 ]Department of Surgical Pathology, Hyogo Medical College, 1-1, Mukogawa-cho, Nishinomiya City, Hyogo 663-8501 Japan
          [49 ]Department of Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577 Japan
          [50 ]Clinical Biochemistry Group, Department of Biochemistry & Molecular Biology, University of Gujrat, Punjab, Pakistan
          [51 ]Department of Health Information Management, College of Applied Medical Sciences, Buraydah Colleges, Al Qassim, Saudi Arabia
          [52 ]Department of Medical Laboratory, College of Applied Medical Sciences, Buraydah Colleges, Al Qassim, Saudi Arabia
          [53 ]King Fahd Medical Research Centre, KAU, Jeddah, Kingdom of Saudi Arabia
          [54 ]Department of Pathology, Faculty of Medicine, KAU, Jeddah, Kingdom of Saudi Arabia
          [55 ]Centre for Excellence in Genomic Medicine Research, Jeddah, Kingdom of Saudi Arabia
          [56 ]Department of Urology, King Faisal Specialist Hospital and research Centre, Jeddah, Kingdom of Saudi Arabia
          [57 ]Department of Urology, KAUH, Jeddah, Kingdom of Saudi Arabia
          [58 ]Research’s Laboratory of Human Genome and Multi-factorial diseases LR12ES07, College of Pharmacy, Monastir, 5000 Tunisia
          [59 ]Faculty of Sciences, Bizerte, 7021 Tunisia
          [60 ]Maternity and Neonatal Centre, Monastir, 5000 Tunisia
          [61 ]Department of Medical Biochemistry, College of Medicine and Medical Sciences, Arabian Gulf University, P.O. Box 22979, Manama, Bahrain
          [62 ]Sidra Medical and Research Center, PO Box 26999, Doha, Qatar
          [63 ]Laboratory of Human Genome and Multifactorials diseases, Faculty of Pharmacy, Monastir, Tunisia
          [64 ]Center of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [65 ]Research Unit Extracellular Matrix and Cellular Dynamic, Faculty of Pharmacy, Monastir, Tunisia
          [66 ]King Fahd Medical Research Centre, KAU, Jeddah, Saudi Arabia
          [67 ]Department of Urology, King Faisal Specialist Hospital and research Centre, Jeddah, Saudi Arabia
          [68 ]Department of Urology, KAUH, Jeddah, Saudi Arabia
          [69 ]Centre for Excellence in Genomic Medicine Research, Jeddah, Saudi Arabia
          [70 ]Department of Pathology, Faculty of Medicine, KAU, Jeddah, Saudi Arabia
          [71 ]Human Genome and Multifactorial Diseases Laboratory, Faculty of Pharmacy, University of Monastir, Monastir, 5000 Tunisia
          [72 ]Faculty of Science of Bizerte, University of Carthage, Jarzouna, 7021 Tunisia
          [73 ]Research Unit: Colorectal cancer in Young Subjects - Faculty of Medecine, University of Monastir, Monastir, 5000 Tunisia
          [74 ]Surgery Department, University Hospital Fattouma Bourguiba, University of Monastir, Monastir, 5000 Tunisia
          [75 ]Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia
          [76 ]Obstertics and Gynaecology Department, Maternity and Children Hospital, Jeddah, Kingdom of Saudi Arabia
          [77 ]Hygiene and Zoonoses Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 35516 Egypt
          [78 ]Bacteriology, Mycology and Immunology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 35516 Egypt
          [79 ]Animal Husbandry and Animal Wealth Development Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 35516 Egypt
          [80 ]Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, PO Box 7607, Holy Makkah, Kingdom of Saudi Arabia
          [81 ]Department of Pharmacology, Faculty of Medicine, Assiut University, Asyut, Egypt
          [82 ]Department of Bioengineering, College of Engineering, Hanyang University, 222 Wangsinmi-ro, Seongdong-gu, Seoul, 133-791 Republic of Korea
          [83 ]Department of Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, PO Box 7607, Saudi Arabia
          [84 ]Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, PO Box 7607, Holy Makkah, Saudi Arabia
          [85 ]Department of Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt
          [86 ]Department of Clinical Nutrition, Faculty of Applied Medical Sciences, Umm Al-Qura University, PO Box 7607, Holy Makkah, Saudi Arabia
          [87 ]Biology Department, College of Education, Iraqia University, Baghdad, Iraq
          [88 ]Biotechnology Research Center, Al- Nahrain University, Baghdad, Iraq
          [89 ]College of dentistry, Baghdad University, Baghdad, Iraq
          [90 ]Department of Physiology, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia
          [91 ]Centre for Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [92 ]King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [93 ]Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK
          [94 ]Security Forces Hospital, General Directorate of Medical Services, Ministry of Interior, Makkah, Kingdom of Saudi Arabia
          [95 ]Department of Biochemistry, Faculty of Science, The M.S. University of Baroda, Vadodara, 390 002 Gujarat India
          [96 ]Department of Skin andVD, Sir Sayajirao Gaikwad Medical College, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat India
          [97 ]Human Cytogenetics Department, National Research Centre, Dokki, Egypt
          [98 ]Clinical Genetics Department, National Research Centre, Dokki, Egypt
          [99 ]Department of Biochemistry, College of Medicine, University of Hail, Hail, Saudi Arabia
          [100 ]Department of Health Information Management, College of Applied Medical Sciences, Buraydah Colleges, Al Qassim, Saudi Arabia
          [101 ]Department of Biosciences, Faculty of Applied Science, Integral University, Lucknow, India
          [102 ]Laboratory of molecular and cellular Hematology, Pasteur Institute of Tunis, University of Tunis El-Manar, 74 PO Box. 1002, Belvedere, Tunis, Tunisia
          [103 ]Service d’Immuno-Hématologie pédiatrique, Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
          [104 ]Department of Molecular Biology, National Cancer Institute (NCI-UG), University of Gezira, Wad Madani, Sudan
          [105 ]Department of Biochemistry and Nutrition, Faculty of Medicine, University of Gezira, Wad Madani, Sudan
          [106 ]Department of Biochemistry, Orotta School of Medicine and Dentistry, ᅟ, Eritrea
          [107 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [108 ]College of Medicine, Institute for Research and Medical Consultations, University of Dammam, Dammam, Saudi Arabia
          [109 ]Clinical Genetics Department, National Research Centre, Cairo, 12622 Egypt
          [110 ]Cytogenetics Department, National Research Centre, Cairo, 12622 Egypt
          [111 ]Biochemistry Department, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [112 ]Biological Sciences Department - Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [113 ]Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [114 ]Flow Cytometry Core Facility, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD USA
          [115 ]Biotechnology and Genetic Engineering Research Unit, Deanship of Scientific Research, Taif University, Taif, Kingdom of Saudi Arabia
          [116 ]Department of Genetics, Faculty of Agriculture and Natural Resources, Aswan University, Aswan, Egypt
          [117 ]College of Biotechnology, Misr University for Science and Technology, Sixth of October City, Egypt
          [118 ]Sheikh Salem Bin Mahfouz Scientific Chair for Treatment of Osteoarthritis by Stem Cells, King Abdulaziz University, Jeddah, Saudi Arabia
          [119 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [120 ]Department of Hematology, Faculty of Medicine, King Abdulaziz University Hospital, King Abdulaziz University, Jeddah, Saudi Arabia
          [121 ]Department of Orthopedic Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [122 ]Stem Cell Unit, Centre of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [123 ]Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [124 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, PO Box 80216, Jeddah, 21589 Saudi Arabia
          [125 ]Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA 19122 USA
          [126 ]Department of Biology, Genomic and Biotechnology Section, King Abdulaziz University, Jeddah, Saudi Arabia
          [127 ]Princess Al-Jawhara Al-Ibrahim Centre of Excellence in Research of Hereditary Disorders, Faculty of Medicine, King Abdul-Aziz University, Jeddah, Saudi Arabia
          [128 ]Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [129 ]Future Scientist Program Trainee at Genetics Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
          [130 ]Department of Biostatistics, Epidemiology and Scientific Computing, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
          [131 ]University of Wolverhampton, Wolverhampton, West Midlands WV1 1LY UK
          [132 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [133 ]Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [134 ]Sheikh Salem Bin Mahfouz Scientific Chair for Treatment of Osteoarthritis by Stem Cells, King Abdulaziz University, Jeddah, Saudi Arabia
          [135 ]Stem Cells Unit, Center of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia
          [136 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [137 ]Department of Orthopaedic Surgery, Faculty of Medicine, King Abdulaziz University Hospital, King Abdulaziz University, Jeddah, Saudi Arabia
          [138 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [139 ]Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA 19122 USA
          [140 ]Medical Laboratories Technology Department, Applied Medical Science College, Taibah University, Al Madinah, Al Munawarah, Saudi Arabia
          [141 ]Center for Genetics and Inherited Diseases, Taibah University, Al Madinah, Al Munawarah, Saudi Arabia
          [142 ]American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH USA
          [143 ]Physiology, Universiti Teknologi, Sungai Buloh, MARA, Malaysia
          [144 ]Redox Biology Laboratory, School of Life Science, Ravenshaw University, Orissa, India
          [145 ]Center of Excellence in Genomic Medicine Research, Jeddah, Saudi Arabia
          [146 ]KACST Center of Innovation in Personalized Medicine at King Abdulaziz University, Jeddah, Saudi Arabia
          [147 ]Urology Department, Cleveland Clinic, Cleveland, OH USA
          [148 ]American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, Ohio USA
          [149 ]Redox Biology Laboratory, School of Life Science, Ravenshaw University, Orissa, India
          [150 ]Physiology, Universiti Teknologi MARA, Sungai Buloh, Malaysia
          [151 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [152 ]KACST Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [153 ]Urology Department, Cleveland Clinic, Cleveland, OH USA
          [154 ]American Center For Reproductive Medicine, Cleveland Clinic, Cleveland, OH USA
          [155 ]Redox Biology Laboratory, School of Life Science, Ravenshaw University, Orissa, India
          [156 ]Institute of Toxicology, Third Military Medical University, Chongqing, China
          [157 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [158 ]KACST Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [159 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, 21589 Saudi Arabia
          [160 ]Department of Obstetrics and Gynecology, King Abdulaziz University Hospital, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589 Saudi Arabia
          [161 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, 21589 Saudi Arabia
          [162 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, PO BOX 80216, Jeddah, 21589 Saudi Arabia
          [163 ]Department of Urology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [164 ]Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [165 ]Department of Pathology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
          [166 ]King Fahd Medical Research Center, King Abdulaziz University, PO BOX 80216, Jeddah, 21589 Saudi Arabia
          [167 ]Zoology Department, Women’s College for Arts, Science & Education, Ain Shams University, Cairo, Egypt
          [168 ]Biology Department, Faculty of Applied Science, Umm Al- Qura University, Makka, Saudi Arabia
          [169 ]Zoology Department, Faculty of Science, Al-Azhar University, Cairo, Egypt
          [170 ]Biotechnology Department, Faculty of Science, Taif University, Taif, Saudi Arabia
          [171 ]King Abdullah University of Science and Technology (KAUST), Computer, Electrical and Mathematical Sciences and Engineering Division, Thuwal, 23955-6900 Saudi Arabia
          [172 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, PO Box 80216, Jeddah, 21589 Saudi Arabia
          [173 ]King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center, Thuwal, Jeddah, 23955-6900 Saudi Arabia
          [174 ]Department of Pathology, King Abdulaziz University, Jeddah, Saudi Arabia
          [175 ]Department of Pathology, Faculty of Medicine, Minia University, Al Minia, Egypt
          [176 ]Department of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [177 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [178 ]Department of Pathology, King Abdulaziz University, Jeddah, Saudi Arabia
          [179 ]Department of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [180 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [181 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, P.O. Box 80216, Jeddah, 21589 Saudi Arabia
          [182 ]Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA 19122 USA
          [183 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [184 ]Stem Cells Unit, Centre of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia
          [185 ]Sheikh Salem Bin Mahfouz Scientific Chair for Treatment of Osteoarthritis by Stem Cells, King Abdulaziz University, Jeddah, Saudi Arabia
          [186 ]Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [187 ]Department of Orthopaedic Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [188 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [189 ]Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia
          [190 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [191 ]KACST Technology Innovation Center in Personalized Medicine at King AbdulAziz University, Jeddah, Saudi Arabia
          [192 ]Dental public health department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia
          [193 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [194 ]Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [195 ]Sheikh Salem Bin Mahfouz Scientific Chair for Treatment of Osteoarthritis by Stem Cells, King Abdulaziz University, Jeddah, Saudi Arabia
          [196 ]Stem Cells Unit, Centre of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia
          [197 ]Department of Orthopaedic Surgery, Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [198 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [199 ]Department of Medicine, University of Health Science, Lahore, Pakistan
          [200 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [201 ]Department of Biology, King Abdul-Aziz University, Jeddah, Saudi Arabia
          [202 ]Center of Innovation in Personalized Medicine at King Abdulaziz University, Jeddah, Saudi Arabia
          [203 ]King Fahd Medical Research Center, King Abdul Aziz University, Jeddah, Saudi Arabia
          [204 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [205 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [206 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [207 ]Center of Innovation in Personalized Medicine at King Abdulaziz University, Jeddah, Saudi Arabia
          [208 ]Bioinformatics Group, Centre of Biotechnology of Sfax, Sfax, Tunisia
          [209 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [210 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [211 ]Department of Cell Biology, The University of Texas Southwestern Medical Center, Dallas, TX USA
          [212 ]Zoology Department, College of Sciences, King Saud University, Riyadh, Saudi Arabia
          [213 ]Institute of Applied Genetics, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, Fort Worth, TX 76107 USA
          [214 ]Institute of Gene Technology, Department of Molecular Diagnostics, Tallinn University of Technology, Akadeemia tee 15A-604, Tallinn, 12618 Estonia
          [215 ]Laboratory of Forensic Anthropology, Center for Human Identification, Department of Biological Sciences, University of North Texas, 1511 West Sycamore, Denton, Texas USA
          [216 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [217 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [218 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [219 ]Urology Department, College of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [220 ]Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH USA
          [221 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, PO Box 80216, Jeddah, 21589 Saudi Arabia
          [222 ]Department of Urology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [223 ]Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [224 ]Department of Pathology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
          [225 ]King Fahd Medical Research Center, King Abdulaziz University, PO Box 80216, Jeddah, 21589 Saudi Arabia
          [226 ]Department of Biochemistry, Ibn Sina National College for Medical Sciences, Jeddah, 21418 Kingdom of Saudi Arabia
          [227 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, 21589 Kingdom of Saudi Arabia
          [228 ]Toxicogemics Laboratory, Division of Genetics, Department of Zoology, Aligarh Muslim University, Aligarh, India
          [229 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, 21589 Kingdom of Saudi Arabia
          [230 ]Center of Excellence in Genomic Medicine (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia
          [231 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [232 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [233 ]Department of Multimedia Technology, Karunya University, Coimbatore, India
          [234 ]Faculy of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [235 ]Centre of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [236 ]Centre of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [237 ]Faculty of Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [238 ]Pediatric Cardiology Department, King Abdulaziz University, Jeddah, Saudi Arabia
          [239 ]Children Hospital, Genetics Department, Ministry of Health, Taif, Saudi Arabia
          [240 ]Cardiology Unit, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [241 ]Gene-Tox Laboratory, Division of Genetics, Department of Zoology, Aligarh Muslim University, Aligarh, UP India
          [242 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [243 ]Diagnostic Genomic Medicine Unit, Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [244 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [245 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [246 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [247 ]Centre of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia
          [248 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [249 ]Department of Obstetrics and Gynaecology, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [250 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [251 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [252 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [253 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [254 ]Department of Medical Genetics, King Fahad General Hospital, Jeddah, Saudi Arabia
          [255 ]Children Hospital, Taif, Saudi Arabia
          [256 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [257 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [258 ]King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [259 ]Mohammad Ali Jauhar University, Rampur, UP India
          [260 ]Center for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi India
          [261 ]Department of Computer Science, Jamia Millia Islamia, Jamia Nagar, New Delhi India
          [262 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [263 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [264 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [265 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [266 ]Jamia Millia Islamia, New Delhi, India
          [267 ]Department of Biotechnology, Kadi Sarva Vishwavidhyalaya, Gandhinagar, Gujarat India
          [268 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [269 ]Clinical Biochemistry Department, College of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [270 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [271 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [272 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [273 ]Obstetrics and Gynecology Department, King AbdulAziz University Hospital, Jeddah, Saudi Arabia
          [274 ]Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [275 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [276 ]Applied Medical Science Laboratory Department, King Abdulaziz University, Jeddah, Saudi Arabia
          [277 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [278 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, 21589 Jeddah, Kingdom of Saudi Arabia
          [279 ]Department of Medical Genetics, King Fahad General Hospital, Jeddah, 21196 Saudi Arabia
          [280 ]Department of Pediatric Neurologist, Maternity and Children Hospital, Jeddah, Saudi Arabia
          [281 ]The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario M5G 1L7 Canada
          [282 ]McLaughlin Centre and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 1L7 Canada
          [283 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [284 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [285 ]Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [286 ]Biochemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia
          [287 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [288 ]Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [289 ]Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [290 ]Department of Genetic Medicine and Development, Medical School, University of Geneva, Geneva, Switzerland
          [291 ]Medical Biochemistry Departments, Faculty of Medicine, Menoufia University, Shibin Al Kawm, Egypt
          [292 ]Departments of Cardiology, Faculty of Medicine, Menoufia University, Shibin Al Kawm, Egypt
          [293 ]Departments of Anesthesia, Faculty of Medicine, Menoufia University, Shibin Al Kawm, Egypt
          [294 ]Biochemistry Departments, Faculty of Medicine, Umm Al-Qura University, Makkha, Kingdom of Saudi Arabia
          [295 ]Center of Innovations in Personalized Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [296 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [297 ]Diabetes & Endocrinology Center of Excellence, Clinical Nutrition Department, International Medical Center, Jeddah, Kingdom of Saudi Arabia
          [298 ]Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [299 ]Special Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, 21589 Kingdom of Saudi Arabia
          [300 ]Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [301 ]Center of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, 21589 Saudi Arabia
          [302 ]Department of Medical Microbiology and Parasitology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [303 ]Department of Anatomical pathology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [304 ]Department of Microbiology, King Abdulaziz University, Jeddah, Saudi Arabia
          [305 ]Department of Computer Science, Faculty of computing and Information Technology Rabigh, King Abdulaziz University, Rabigh, 21911 Saudi Arabia
          [306 ]Kusuma School of biological Sciences, Indian Institute of Technology, Delhi (IITD), Hauz Khas, New Delhi, 110016 India
          [307 ]Mathematics Department, Faculty of Sciences, King Abdul Aziz University, P. O. Box 80003, Jeddah, 21589 Saudi Arabia
          [308 ]Department of Information Technology, Faculty of computing and Information Technology Rabigh, King Abdulaziz University, Rabigh, 21911 Saudi Arabia
          [309 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [310 ]Center of Innovation in Personalized Medicine, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [311 ]Biochemistry Department, Faculty of Science, Production of Bioproducts for Industrial Applications Research Group and Experimental Biochemistry Unit, King Fahd Medical Research Center King, Abdulaziz University, Jeddah, Saudi Arabia
          [312 ]Department of Agriculture, Faculty of Agricultural and Food Sciences, American University of Beirut (AUB), Beirut, Lebanon
          [313 ]Adjuncted to Biochemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia
          [314 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [315 ]Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia
          [316 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [317 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [318 ]Deaprtment of Computer Science, Faculty of computing and Information Technology Rabigh, King Abdulaziz University, Rabigh, 21911 Saudi Arabia
          [319 ]Department of Information Systems, Faculty of computing and Information Technology Rabigh, King Abdulaziz University, Rabigh, 21911 Saudi Arabia
          [320 ]Department of Medical Laboratory Technology and Haematology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [321 ]Centre of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [322 ]Sheikh Salem Bin Mahfouz Scientific Chair for Treatment of Osteoarthritis by Stem Cells, King Abdulaziz University, Jeddah, Saudi Arabia
          [323 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [324 ]Department of Orthopaedic Surgery, Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [325 ]Center of Excellence in Genomic Medicine Research, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [326 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [327 ]Biochemistry Department, Faculty of Science, Production of Bioproducts for Industrial Applications Research Group and Experimental Biochemistry Unit, King Fahd Medical Research Center King, Abdulaziz University, Jeddah, Saudi Arabia
          [328 ]King Fahd Medical Research Center, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [329 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [330 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [331 ]Department of Environmental sciences, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, Jeddah, Saudi Arabia
          [332 ]New York University School of Medicine, Nelson Institute of Environmental Medicine, New York, USA
          [333 ]Centre of Biotechnology of Sfax, Laboratory of Molecular and Cellular Screening Processes, Bioinformatics Group, Po. Box: 1177, 3018 Sfax, Tunisia
          [334 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [335 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [336 ]King Fahd Medical Research Centre (KFMRC), King Abdulaziz University, Jeddah, Saudi Arabia
          [337 ]Centre of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia
          [338 ]Aziziah Maternity and Children Hospital, Jeddah, Saudi Arabia
          [339 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [340 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [341 ]Sheikh Salem Bin Mahfouz Scientific Chair for Treatment of Osteoarthritis by Stem Cells, King Abdulaziz University, Jeddah, Saudi Arabia
          [342 ]Department of Orthopaedic Surgery, Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [343 ]The D-BOARD European Consortium for Biomarker Discovery, The APPROACH Innovative Medicines Initiative (IMI) Consortium, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey GU2 7XH UK
          [344 ]Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis, Arthritis Research UK Pain Centre, Medical Research Council and Arthritis Research UK Centre for Musculoskeletal Ageing Research, University of Nottingham, Queen’s Medical Centre, Nottingham, NG7 2UH UK
          [345 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [346 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [347 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [348 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [349 ]Department of Multimedia Technology, Karunya University, Coimbatore, India
          [350 ]King Fahad Center for Medical Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [351 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [352 ]Department of Biological Sciences, College of Science and Arts-Rabigh, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [353 ]Center of Emphasis in Neuroscience, Texas Tech University Health Science Center, El Paso, 79905 Texas USA
          [354 ]Faculty of Computing and Information Technology, King Abdulaziz University, Rabigh, 21911 Kingdom of Saudi Arabia
          [355 ]Department of Biological Sciences and Engineering, Maulana Azad National Institute of Technology, Bhopal, 462051 India
          [356 ]Faculty of Computing and Information Technology, King Abdulaziz University, Rabigh, Saudi Arabia
          [357 ]Department of Biotechnology, KadiSarvaVishwavidhyalaya, Gandhinagar, Gujarat India
          [358 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [359 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [360 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [361 ]Faculty of Computing and Information Technology, King Abdulaziz University, Rabigh, Kingdom of Saudi Arabia
          [362 ]Department of Obstetrics and Gynecology, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [363 ]KACST Technology Innovation Center in Personalized Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [364 ]Department of Clinical and Chemical Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt
          [365 ]Cardiogenetic Team, Department of Pediatrics, College of Medicine, Taibah University, AL Madinah, Saudi Arabia
          [366 ]Department of Human Genetics, Medical Research Institute, Alexandria University, Alexandria, Egypt
          [367 ]Department of Cardiology, Faculty of Medicine, Tanta University, Tanta, Egypt
          [368 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [369 ]Centre for Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [370 ]Centre for Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [371 ]Center of Excellence for Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [372 ]Biochemistry Department, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [373 ]Special Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [374 ]Medical Laboratory Technology Department, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [375 ]Department of Obstetrics & Gynaecology, King Abdul Aziz University Hospital, Jeddah, Saudi Arabia
          [376 ]Faculty of Agriculture, American University of Beirut, Beirut, Lebanon
          [377 ]Adjunct to Biochemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia
          [378 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [379 ]Center of Innovation in Personalized Medicine, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [380 ]Biochemistry Department, Faculty of Science, Abdulaziz University, Jeddah, Saudi Arabia
          [381 ]Production of Bioproducts for Industrial Applications Research Group, Abdulaziz University, Jeddah, Saudi Arabia
          [382 ]Experimental Biochemistry Unit, King Fahd Medical Research Center King, Abdulaziz University, Jeddah, Saudi Arabia
          [383 ]Department of Agriculture, Faculty of Agricultural and Food Sciences, American University of Beirut (AUB), Beirut, Lebanon
          [384 ]adjuncted to Biochemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia
          [385 ]Clinical Pathology Department, Mansoura University, Faculty of Medicine, Mansoura, Egypt
          [386 ]Rheumatology and Rehabilitation Department, Mansoura University, Faculty of Medicine, Mansoura, Egypt
          [387 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [388 ]KACST Technology Innovation Center in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [389 ]Children Hospital, Genetics Department, Taif, Saudi Arabia
          [390 ]Aziziah Maternity and Children Hospital, Jeddah, Saudi Arabia
          [391 ]The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Canada
          [392 ]King Fahd Medical Research Center, King Abdulaziz University, P.O. Box 80216, Jeddah, 21589 Saudi Arabia
          [393 ]Department of Biophysics, All India Institute of Medical Sciences, New Delhi, 110029 India
          [394 ]Children’s Hospital of Philadelphia, Philadelphia, PA 19104 USA
          [395 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, P.O. Box 80216, Jeddah, 21589 Saudi Arabia
          [396 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [397 ]Department of Biology, King Abdulaziz University, Jeddah, Saudi Arabia
          [398 ]King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [399 ]KACST Technology Innovation Center in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [400 ]Department of Pathology, Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [401 ]Department of Pathology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
          [402 ]Division of Neurosurgery, Department of Surgery, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [403 ]Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [404 ]Centre of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia
          [405 ]Experimental Biochemistry Unit, King Fahd Medical Research Centre King, Abdulaziz University, Jeddah, Saudi Arabia
          [406 ]Department of Medical Genetics, Umm Al-Qura University, Makkah, Saudi Arabia
          [407 ]Science and Technology Unit, Umm Al-Qura University, Makkah, Saudi Arabia
          [408 ]Department of Laboratory and Blood Bank, King Abdullah Medical City, Makkah, Saudi Arabia
          [409 ]King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
          [410 ]Center of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia
          [411 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [412 ]Gynecological Oncology Unit, Department of Obstetrics and Gynaecology, Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [413 ]Laboratory of Biotechnology and Valorization of Bio/Geo Resources LR11ES31 High Institute of Biotechnology Sidi Thabet, University of Manouba, Biotechpole, Sidi Thabet, Tunisia
          [414 ]Department of Gastroenterology, Hospital Mohamed Taher Maamouri, Nabeul, Tunisia
          [415 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [416 ]Center of Innovation in Personalized Medicine, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [417 ]Biochemistry Department, Faculty of Science, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [418 ]Production of Bioproducts for Industrial Applications Research Group, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [419 ]Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [420 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [421 ]Center of Excellence in Genomic medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [422 ]Biology Department, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [423 ]Medical Laboratory Department, Faculty of Applied Medical Technology, King Abdulaziz University, Jeddah, Saudi Arabia
          [424 ]Diagnostic Genomic Medicine Unit, Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [425 ]Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [426 ]Department of Biochemistry, King Abdulaziz University, Jeddah, Saudi Arabia
          [427 ]Production of Bioproducts for Industrial Applications Research Group and Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [428 ]Microbial Biotechnology Department, National Research Center, Dokki, Cairo, Egypt
          [429 ]Centre for Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [430 ]Center of Excellence in Genomic Medicine, King Abdulaziz University, PO Box 80216, Jeddah, 21589 Saudi Arabia
          [431 ]Institute for Genomics and Evolutionary Medicine, Temple University (SERC 602A), Philadelphia, Pennsylvania 19122 USA
          [432 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [433 ]Department of Biology, King Abdulaziz University, Jeddah, Saudi Arabia
          [434 ]King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [435 ]Department of Pathology, Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [436 ]Department of Pathology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
          [437 ]Division of Neurosurgery, Department of Surgery, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [438 ]KACST Technology Innovation Center in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [439 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [440 ]King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [441 ]KACST Technology Innovation Center in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [442 ]Department of Pathology, Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [443 ]Department of Pathology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
          [444 ]Division of Neurosurgery, Department of Surgery, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
          [445 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [446 ]KACST Technology Innovation Center in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [447 ]Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [448 ]Department of Surgery, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
          [449 ]Department of Pathology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
          [450 ]Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [451 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [452 ]KACST Technology Innovation Center in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [453 ]Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [454 ]Department of Surgery, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
          [455 ]Department of Pathology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
          [456 ]Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [457 ]Biology Department, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [458 ]Special Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [459 ]Medical Laboratory Technology Department, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [460 ]Laboratory of Biotechnology and Valorization of Bio/Geo Resources LR11ES31 High Institute of Biotechnology Sidi Thabet, University of Manouba, Biotechpole Sidi Thabet, Sidi Thabet, Tunisia
          [461 ]Department of Gastroenterology, Hospital Mohamed Taher Maamouri, Nabeul, Tunisia
          [462 ]Laboratory of Soil Biology, University Neuchatel, Neuchatel, Switzerland
          [463 ]Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
          [464 ]Center of Innovation in Personalized Medicine, King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [465 ]Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
          [466 ]Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [467 ]Centre of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [468 ]Hôpital Necker-Enfants Malades-Université Paris descartes-Laboratoire de génétique, Paris, France
          [469 ]Erfan & Bagedo Hospital, Jeddah, Saudi Arabia
          [470 ]Aziziah Maternity and Children Hospital, Jeddah, Saudi Arabia
          [471 ]Center of Excellence in Genomic Medicine Research (CEGMR), King Abdullaziz University, Jeddah, Saudi Arabia
          [472 ]Department of Clinical Genetic and Metabolic Genetics, King Saud Medical Hospital, Riyadh, Saudi Arabia
          [473 ]Department of Pathology, School of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia
          [474 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [475 ]Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
          [476 ]King Abdullah International Medical Research Center/King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyad, Saudi Arabia
          [477 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [478 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia
          [479 ]Department of Biosciences, Jamia Milia Islamia, New Delhi, India
          [480 ]Mohammad Ali Jauhar University, Rampur, UP India
          [481 ]School of Medicine, University of Health Science, Lahore, Pakistan
          [482 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          [483 ]Department of Biology, King Abdul-Aziz University, Jeddah, Saudi Arabia
          [484 ]Center of Innovation in Personalized Medicine at King Abdulaziz University, Jeddah, Saudi Arabia
          [485 ]King Fahd Medical Research Center, King Abdul Aziz University, Jeddah, Saudi Arabia
          [486 ]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [487 ]Centre of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [488 ]KACST Technology Innovation Center in Personalized Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
          [489 ]Department of Obstetrics and Gynecology, King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia
          [490 ]Medical Biotechnology and Translational Medicine Research, King Fahd Medical Research Center, King Abdulaziz University, PO Box 80216, Jeddah, 21589 Saudi Arabia
          [491 ]Institute of Microbial Technology (IMTECH), Chandigarh, 160036 India
          [492 ]Ummul Qura University, Makkah, Saudi Arabia
          [493 ]Center of Excellence in Genomic Medicine Research, King Abdulaziz University, P.O. Box 80216, Jeddah, 21589 Saudi Arabia
          [494 ]Department of Biochemistry, Faculty of Medicine, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia
          [495 ]Department of Biochemistry, Faculty of Pharmacy, Al-Azhar University, 71524 Assiut, Egypt
          [496 ]Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany
          [497 ]Assisted Conception Unit, Obstetrics and Gynecology Department, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia
          [498 ]Urology Division, Surgery Department, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia
          [499 ]Toxicogenomics Laboratory, Division of Genetics, Department of Zoology, Aligarh Muslim University, Aligarh, India
          [500 ]Centre of Excellence in Genomic and Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
          Article
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          10.1186/s12864-016-2858-0
          4959372
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          25ed84dd-2bb8-4ebb-9fcd-4cf6ed42faf0
          © The Author(s). 2016

          Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

          The 3rd International Genomic Medicine Conference (3rd IGMC 2015)
          Jeddah, Kingdom of Saudi Arabia
          30 November - 3 December 2015
          History
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          Genetics
          Genetics

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