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Isolation and Characterization of Viruses Related to the SARS Coronavirus from Animals in Southern China
October 10 2003
October 10 2003
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Abstract
A novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome
(SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal
market in Guangdong, China. Evidence of virus infection was also detected in other
animals (including a raccoon dog, Nyctereutes procyonoides) and in humans working
at the same market. All the animal isolates retain a 29-nucleotide sequence that is
not found in most human isolates. The detection of SCoV-like viruses in small, live
wild mammals in a retail market indicates a route of interspecies transmission, although
the natural reservoir is not known.