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      A New Method of Measuring in vivo the Lens Transmittance, and Study of Lens Scatter, Fluorescence and Transmittance

      Ophthalmic Research
      S. Karger AG
      Lens, Fluorescence, Scatter, Photometry, Diabetes, Transmittance

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          We propose a new method to measure in vivo nuclear transmittance using scanning photometry, thus complementing its present application in measuring lens scatter and fluorescence. We compared our method of measuring the transmittance with a previously reported in vivo method and found an adequate correlation. We then measured the fluorescence, scatter and transmittance of lenses without cataract and those with as much as a mild yellowing. The three phenomena correlated with age. In addition, this study allowed a correlation of the three phenomena with each other, indicating that the loss of transmittance of the nucleus cannot be explained by its thickening alone but that changes in its composition must take place. Finally, a preliminary study on diabetics showed early onset of the process responsible for the increase in lens fluorescence. This process did not seem to be accelerated in diabetics in comparison with normals. The nuclear scatter appeared to increase more rapidly with age in nondiabetics as compared to diabetics. This preliminary study suggests mainly that scanning photometry can be used to study aging and pathologic changes in the lens.

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          Author and article information

          Ophthalmic Res
          Ophthalmic Research
          S. Karger AG
          04 December 2009
          : 16
          : 5
          : 246-255
          Department of Ophthalmology, University of Illinois, Eye and Ear Infirmary, Chicago, III. USA
          265325 Ophthalmic Res 1984;16:246–255
          © 1984 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          : 16 August 1983
          : 21 December 1983
          Page count
          Pages: 10
          Original Paper

          Vision sciences,Ophthalmology & Optometry,Pathology


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