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      Energy response of EBT3 radiochromic films: implications for dosimetry in kilovoltage range

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          Abstract

          The objective of this study is to evaluate the suitability of recently introduced radiochromic film EBT3 for clinical dosimetry in the kilovoltage (kV) range. For this purpose, a kV X‐ray irradiator, X RAD 320ix in the range 70 to 300 kVp, a clinical 60 Co source, a 6 MV and an 18 MV X‐ray clinical beam from a Varian linear accelerator were calibrated following AAPM dosimetry protocols. EBT3 films from two different EBT3 batches were placed side‐by‐side on the surface of a water phantom; doses from 0.5 to 4 Gy were delivered. Similarly, irradiations were performed for 60 Co and 6 and 18 MV beams in a water‐equivalent phantom. Films were reproducibly placed at the center of a flatbed scanner and 48‐bit RGB scans were obtained both pre‐ and postirradiations. Net optical density (netOD) and response for a given radiation quality relative to 60 Co was determined for each EBT3 film. The netOD of the red color showed reproducible response (within 1%) for both batches when irradiated using the 60 Co source. For a given dose of 1 Gy of kVp X‐ray, the response relative to 60 Co using the three color channels (red, green, and blue) decreases with decrease in kVp, reaching a maximum underresponse of 20 % for the 70 kVp. A significant underresponse of 5 % was observed at 300 kVp. Responses of MV X‐ray beams with respect to 60 Co at the 1 Gy dose level showed no statistically significant difference. A relatively small difference in the response was observed between the two EBT3 batches used in this study in the kV X‐ray range.

          PACS numbers: 87.56.B, 87.57.uq

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          Most cited references9

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          Multichannel film dosimetry with nonuniformity correction.

          A new method to evaluate radiochromic film dosimetry data scanned in multiple color channels is presented. This work was undertaken to demonstrate that the multichannel method is fundamentally superior to the traditional single channel method. The multichannel method allows for the separation and removal of the nondose-dependent portions of a film image leaving a residual image that is dependent only on absorbed dose. Radiochromic films were exposed to 10 x 10 cm radiation fields (Co-60 and 6 MV) at doses up to about 300 cGy. The films were scanned in red-blue-green (RGB) format on a flatbed color scanner and measured to build calibration tables relating the absorbed dose to the response of the film in each of the color channels. Film images were converted to dose maps using two methods. The first method used the response from a single color channel and the second method used the response from all three color channels. The multichannel method allows for the separation of the scanned signal into one part that is dose-dependent and another part that is dose-independent and enables the correction of a variety of disturbances in the digitized image including nonuniformities in the active coating on the radiochromic film as well as scanner related artifacts. The fundamental mathematics of the two methods is described and the dose maps calculated from film images using the two methods are compared and analyzed. The multichannel dosimetry method was shown to be an effective way to separate out non-dose-dependent abnormalities from radiochromic dosimetry film images. The process was shown to remove disturbances in the scanned images caused by nonhomogeneity of the radiochromic film and artifacts caused by the scanner and to improve the integrity of the dose information. Multichannel dosimetry also reduces random noise in the dose images and mitigates scanner-related artifacts such as lateral position dependence. In providing an ability to calculate dose maps from data in all the color channels the multichannel method provides the ability to examine the agreement between the color channels. Furthermore, when using calibration data to convert RGB film images to dose using the new method, poor correspondence between the dose calculations for the three color channels provides an important indication that the this new technique enables easy indication in case the dose and calibration films are curve mismatched. The method permit compensation for thickness nonuniformities in the film, increases the signal to noise level, mitigates the lateral dose-dependency of flatbed scanners effect of the calculated dose map and extends the evaluable dose range to 10 cGy-100 Gy. Multichannel dosimetry with radiochromic film like Gafchromic EBT2 is shown to have significant advantages over single channel dosimetry. It is recommended that the dosimetry protocols described be implemented when using this radiochromic film to ensure the best data integrity and dosimetric accuracy.
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            Precise radiochromic film dosimetry using a flat-bed document scanner.

            In this study, a measurement protocol is presented that improves the precision of dose measurements using a flat-bed document scanner in conjunction with two new GafChromic film models, HS and Prototype A EBT exposed to 6 MV photon beams. We established two sources of uncertainties in dose measurements, governed by measurement and calibration curve fit parameters contributions. We have quantitatively assessed the influence of different steps in the protocol on the overall dose measurement uncertainty. Applying the protocol described in this paper on the Agfa Arcus II flat-bed document scanner, the overall one-sigma dose measurement uncertainty for an uniform field amounts to 2% or less for doses above around 0.4 Gy in the case of the EBT (Prototype A), and for doses above 5 Gy in the case of the HS model GafChromic film using a region of interest 2 X 2 mm2 in size.
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              Monte Carlo calculated absorbed-dose energy dependence of EBT and EBT2 film.

              The absorbed-dose energy dependence of GAFCHROMIC EBT and EBT2 film irradiated in photon beams is studied to understand the shape of the curves and the physics behind them.
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                Author and article information

                Contributors
                Eduardo.villrrealbarajas@albertahealthservices.ca
                Journal
                J Appl Clin Med Phys
                J Appl Clin Med Phys
                10.1002/(ISSN)1526-9914
                ACM2
                Journal of Applied Clinical Medical Physics
                John Wiley and Sons Inc. (Hoboken )
                1526-9914
                06 January 2014
                January 2014
                : 15
                : 1 ( doiID: 10.1002/acm2.2014.15.issue-1 )
                : 331-338
                Affiliations
                [ 1 ] Department of Oncology and Department of Physics and Astronomy University of Calgary , Calgary AB
                [ 2 ] Department of Medical Physics Tom Baker Cancer Centre Alberta Canada
                Author notes
                [*] [* ] a Corresponding author: J. Eduardo Villarreal‐Barajas, Department of Medical Physics, Tom Baker Cancer Centre, Calgary, 1331, 29th street NW, Calgary, AB, Canada T2N 4N2; phone: (403) 521 3598; fax: (403) 521 3327; email: Eduardo.villrrealbarajas@ 123456albertahealthservices.ca

                Article
                ACM20331
                10.1120/jacmp.v15i1.4439
                5711253
                24423839
                2648c0aa-c670-4d5d-8a4b-e1a8cd6563c4
                © 2014 The Authors.

                This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 11 March 2013
                : 18 July 2013
                Page count
                Figures: 2, Tables: 4, References: 11, Pages: 8, Words: 3826
                Categories
                Radiation Measurements
                Radiation Measurements
                Custom metadata
                2.0
                acm20331
                January 2014
                Converter:WILEY_ML3GV2_TO_NLMPMC version:5.2.5 mode:remove_FC converted:17.11.2017

                radiochromic film dosimetry,ebt3 films,kilovoltage dosimetry,energy response,orthovoltage dosimetry

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