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      Outcome predictors for treatment success with 5% lidocaine medicated plaster in low back pain with neuropathic components and neuropathic pain after surgical and nonsurgical trauma

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          Five percent lidocaine medicated plaster has been proven efficacious for the symptomatic relief of neuropathic pain in diverse pain conditions which might be attributed to a common localized symptomatology in these indications, possibly with common predictors of treatment success. To discuss potential symptoms and other factors predicting response to treatment with lidocaine plaster for the indications of low back pain with neuropathic components and neuropathic pain after surgical and nonsurgical trauma, 44 pain specialists from 17 countries attended a two-day conference meeting in December 2009. Discussions were based on the retrospective analysis of case reports (sent in by participants in the four weeks prior to the meeting) and the practical experience of the participants. The results indicate some predictors for success with 5% lidocaine medicated plaster for the two indications. Localized pain, hyperalgesia and/or allodynia, and other positive sensory symptoms, such as dysesthesia, were considered positive predictors, whereas widespread pain and negative sensory symptoms were regarded as negative predictors. Paresthesia, diagnosis, and site of pain were considered to be of no predictive value. Common symptomatology with other neurologic pathologies suggests that treatment of localized neuropathic pain symptoms with the plaster can be considered across different neuropathic pain indications.

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                Author and article information

                J Pain Res
                Journal of Pain Research
                Dove Medical Press
                11 January 2011
                : 4
                : 25-38
                [1 ] St Georges Hospital, London, UK
                [2 ] Allentown, Pennsylvania, USA
                [3 ] Antwerp University Hospital, Edegem, Belgium
                [4 ] Institut Curie, Saint Cloud, France
                Author notes
                Correspondence: Guy Hans, Multidisciplinary Pain Center, Antwerp University Hospital, Wilrijkstraat 10, 2650, Edegem, Belgium, Tel +323 821 4945, Fax +323 821 4586, Email guy.hans@ 123456uza.be
                © 2011 Nicolaou et al, publisher and licensee Dove Medical Press Ltd.

                This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.

                Original Research


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