50
views
0
recommends
+1 Recommend
2 collections
    0
    shares

      The APC waiver has been extended to also apply to manuscripts submitted until March 31, 2024.

      To submit to the journal, please click here.

      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Prevalence of Chlamydia trachomatis infection diagnosed by polymerase chain reaction in female sex workers in a Northern Mexican City

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Purpose: We aimed to determine the association between Chlamydia trachomatis infection and female sex work, and the association between sociodemographic, obstetric, and behavioral characteristics of female sex workers and C. trachomatis infection.

          Methods: Through a case–control study design, we studied 201 female sex workers and 201 age-matched women without sex work in Durango City, Mexico. C. trachomatis DNA was detected in cervical swab samples using polymerase chain reaction.

          Results: C. trachomatis DNA was detected in 32 (15.9%) of the 201 cases and in 6 (3.0%) of the 201 controls (odds ratio [OR] = 6.15; 95% confidence interval [CI]: 2.5–15.0; P < 0.001). The frequency of infection with C. trachomatis in female sex workers did not vary ( P > 0.05) regardless of the history of pregnancies, deliveries, cesarean sections, or miscarriages. Regression analysis of the behavioral characteristics showed that infection with C. trachomatis was associated only with consumption of alcohol (OR = 2.39; 95% CI: 1.0–5.71; P = 0.04).

          Conclusions: We conclude that C. trachomatis infection is associated with female sex work in Durango City, Mexico. This is the first age-matched case–control study on the prevalence of C. trachomatis infection in female sex workers in Mexico using detection of C. trachomatis DNA in cervical samples.

          Related collections

          Most cited references16

          • Record: found
          • Abstract: found
          • Article: not found

          Low prevalences of HIV infection and sexually transmitted disease among female commercial sex workers in Mexico City.

          This study tried to determine human immunodeficiency virus (HIV)/sexually transmitted disease (STD) prevalences among female commercial sex workers in Mexico City. A sampling frame was constructed that included bars, massage parlors, and street corners. Prevalences for Treponema pallidum, herpes simplex virus type 2, HIV, Neisseria gonorrhoeae, and Chlamydia trachomatis were 6.4%, 65%, 0.6%, 3.7%, and 11.1%, respectively. A significant association was found between higher STD frequencies and working at street sites. Most STD frequencies were lower in comparison with rates found for female sex workers in other countries. However, preventive programs against STD/ HIV are needed in this population.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Sociodemographic dynamics and sexually transmitted infections in female sex workers at the Mexican-Guatemalan border.

            If the predominant means of HIV transmission is heterosexual in the Soconusco region of Mexico, then the female sex workers (FSWs) from Central America who work in this region may be playing a significant role in the heterosexual transmission of HIV.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found
              Is Open Access

              Host-pathogen reorganisation during host cell entry by Chlamydia trachomatis

              Chlamydia trachomatis is obligate intracellular bacterial pathogen that remains a significant public health burden worldwide. A critical early event during infection is chlamydial entry into non-phagocytic host epithelial cells. Like other Gram-negative bacteria, C. trachomatis uses a type III secretion system (T3SS) to deliver virulence effector proteins into host cells. These effectors trigger bacterial uptake and promote bacterial survival and replication within the host cell. In this review, we highlight recent cryo-electron tomography that has provided striking insights into the initial interactions between Chlamydia and its host. We describe the polarised structure of extracellular C. trachomatis elementary bodies (EBs), and the supramolecular organisation of T3SS complexes on the EB surface, in addition to the changes in host and pathogen architecture that accompany bacterial internalisation and EB encapsulation into early intracellular vacuoles. Finally, we consider the implications for further understanding the mechanism of C. trachomatis entry and how this might relate to those of other bacteria and viruses.
                Bookmark

                Author and article information

                Journal
                1886
                European Journal of Microbiology and Immunology
                EuJMI
                Akadémiai Kiadó
                2062-8633
                March 2019
                : 9
                : 1
                : 5-8
                Affiliations
                [ 1 ]Institute for Scientific Research “Dr. Roberto Rivera-Damm”, Juárez University of Durango State , Avenida Universidad S/N, 34000 Durango, Mexico
                [ 2 ]Departamento de Infectología, Laboratorio de Virología del Instituto Nacional de Perinatología, Departamento de Microbiología de la Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional , D.F México
                [ 3 ]Faculty of Medicine and Nutrition, Juárez University of Durango State , Avenida Universidad S/N, 34000 Durango, Mexico
                Author notes
                [*]

                Author for correspondence: Biomedical Research Laboratory. Faculty of Medicine and Nutrition, Juárez University of Durango State, Avenida Universidad S/N, 34000 Durango, Dgo, Mexico; Tel: +52-618 8130527; Fax: +52-618 8130527; alvaradocosme@ 123456yahoo.com .

                Article
                10.1556/1886.2018.00034
                6444802
                26762fbb-ab2c-4380-8475-a868d230deb7
                © 2019 The Author(s)

                This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and reproduction in any medium for non-commercial purposes, provided the original author and source are credited, a link to the CC License is provided, and changes - if any - are indicated.

                History
                : 30 December 2018
                : 21 January 2019
                : 2 February 2019
                Page count
                Pages: 4
                Categories
                Original Research Paper

                Medicine,Immunology,Health & Social care,Microbiology & Virology,Infectious disease & Microbiology
                case–control study, Chlamydia trachomatis ,prevalence,female sex workers

                Comments

                Comment on this article