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      Measurement of Left Ventricular Mass by Contrast Ventriculography

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          Abstract

          Background

          Elevated left ventricular mass (LVM) has been shown to be an important predictor of adverse cardiac events. Calculation of LVM using contrast ventriculography, as described by Rackley, involves measuring left ventricular wall thickness in a single plane, with assumptions made about ventricular geometry.

          Hypothesis

          We hypothesized that a modification of the Rackley method, involving multiple measurements of left ventricular (LV) wall thickness in 2 orthogonal planes, may add value in the determination of LVM in patients with LV remodeling and dysfunction.

          Methods

          The LVM was determined in 24 patients with LV dysfunction who had undergone both cardiac magnetic resonance imaging (CMRI) and contrast left ventriculography. Right anterior oblique (RAO) and left anterior oblique (LAO) still frames in diastole were used to measure LV length, chamber area, and wall thickness. From these variables, LV volume, myocardial volume, and LVM were calculated. The LVM calculations using an average wall thickness from the LAO and RAO projections were compared with LVM measured by CMRI.

          Results

          Eighty eight percent of patients had hypertension, 100% had coronary artery disease, and mean left ventricular ejection fraction by contrast left ventriculography was 41 ± 14%. Averaging left ventricular wall thickness from RAO and LAO projections using biplane ventriculography for LVM calculation yielded a strong correlation (r = 0.77, p < 0.01) with LVM calculated from CMR.

          Conclusions

          In patients with left ventricular dysfunction, biplane left ventricular wall thickness measurements for contrast ventriculography LVM calculations render a strong correlation with LVM calculated by CMRI. Copyright © 2008 Wiley Periodicals, Inc.

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          Author and article information

          Contributors
          hsamady@emory.edu
          Journal
          Clin Cardiol
          Clin Cardiol
          10.1002/(ISSN)1932-8737
          CLC
          Clinical Cardiology
          Wiley Periodicals, Inc. (New York )
          0160-9289
          1932-8737
          17 July 2008
          July 2008
          : 31
          : 7 ( doiID: 10.1002/clc.v31:7 )
          : 323-327
          Affiliations
          [ 1 ]Cardiovascular Division, Department of Medicine
          [ 2 ]Department of Radiology, University of Virginia Health System, Charlottesville, Virginia, USA
          [ 3 ]Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven
          [ 4 ]Renal Section, VA Connecticut Healthcare System, West Haven, Connecticut
          [ 5 ]Cardiovascular Division, Department of Medicine, Emory University, Atlanta, Georgia, USA
          Author notes
          [*] [* ]Cardiovascular Division Andreas Gruentzig Cardiovascular Center of Emory University Emory University Hospital 1364 Clifton Road NE, Suite F606 Atlanta, GA 30322, USA
          Article
          PMC6653709 PMC6653709 6653709 CLC20223
          10.1002/clc.20223
          6653709
          18636475
          268a897e-7f38-4139-926c-38048a99b1a4
          Copyright © 2008 Wiley Periodicals, Inc.
          History
          : 12 June 2007
          : 16 June 2007
          Page count
          Figures: 3, Tables: 2, References: 14, Pages: 5
          Categories
          Clinical Investigation
          Clinical Investigations
          Custom metadata
          2.0
          July 2008
          Converter:WILEY_ML3GV2_TO_NLMPMC version:5.6.2.1 mode:remove_FC converted:09.05.2019

          diagnostic intervention,hypertrophy,cardiac catheterization,heart failure,cardiac transplantation,cardiomyopathy,myocarditis

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