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      Persistent COVID-19 syndrome. A narrative review Translated title: Síndrome de COVID-19 persistente. Una revisión narrativa

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          Abstract

          As the coronavirus-2019 disease (COVID-19) pandemic, caused by the infection with severe acute respiratory syndrome (SARS-CoV-2) coronavirus type 2, has progressed, persistent COVID-19 syndrome is an increasingly recognized problem on which a significant volume of medical literature is developing. Symptoms may be persistent or appear, after an asymptomatic period, weeks or months after the initial infection. The clinical picture is as markedly heterogeneous and multisystemic as in the acute phase, so multidisciplinary management is required. In addition, their appearance is not related to the severity of the initial infection, so they can affect both mild patients, even asymptomatic, and seriously ill patients who have required hospitalization. Although it can affect people of any age, it is more common in middle-aged women. The sequelae can generate a high impact on the quality of life, and in the work and social environment. The objective of this paper is to review persistent COVID-19 syndrome, to know its clinical manifestations and the strategies for the management and follow-up of these patients.

          Translated abstract

          A medida que ha avanzado la pandemia de la enfermedad por coronavirus-2019 (COVID-19), originada por la infección por el coronavirus de tipo 2, causante del síndrome respiratorio agudo severo (SARS-CoV-2), el síndrome de COVID-19 persistente es un problema cada vez más reconocido y sobre el que se está desarrollando un importante volumen de publicaciones. Los síntomas pueden ser persistentes o aparecer, tras un periodo asintomático, semanas o meses después de la infección inicial. El cuadro clínico es tan marcadamente heterogéneo y multisistémico como en la fase aguda, por lo que se requiere un manejo multidisciplinar. Además, su aparición no está relacionada con la gravedad de la infección inicial, por lo que pueden afectar tanto a pacientes leves, incluso asintomáticos, como a enfermos graves que han requerido hospitalización. Aunque puede afectar a personas de cualquier edad, es más frecuente en mujeres de edad media. Las secuelas pueden generar un elevado impacto en la calidad de vida, y en el ámbito laboral y social. El objetivo de este trabajo es hacer una revisión sobre el síndrome de COVID-19 persistente, conocer sus manifestaciones clínicas y las estrategias para el manejo y seguimiento de estos pacientes.

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          Author and article information

          Journal
          Rev Clin Esp (Barc)
          Rev Clin Esp (Barc)
          Revista Clinica Espanola
          Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI).
          2254-8874
          28 February 2022
          28 February 2022
          Affiliations
          [a ]Servicio de Medicina Interna, Hospital Regional Universitario de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA), Universidad de Málaga (UMA), Málaga, Spain
          [b ]Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain
          Author notes
          [* ]Corresponding author.
          Article
          S2254-8874(22)00008-X
          10.1016/j.rceng.2021.10.001
          8882405
          35260380
          26c6646b-9ca3-4444-b2ec-3beb2c0bade1
          © 2021 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.

          Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

          History
          : 20 August 2021
          : 12 October 2021
          Categories
          Review

          persistent covid-19,post-acute covid,long covid,covid-19 sequels,covid-19 persistente,covid-19 posagudo,covid de larga duración,secuelas covid-19

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