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      A simple sample size formula for analysis of covariance in randomized clinical trials.

      1 , ,
      Journal of clinical epidemiology
      Elsevier BV

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          Abstract

          Randomized clinical trials that compare two treatments on a continuous outcome can be analyzed using analysis of covariance (ANCOVA) or a t-test approach. We present a method for the sample size calculation when ANCOVA is used.

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          Author and article information

          Journal
          J Clin Epidemiol
          Journal of clinical epidemiology
          Elsevier BV
          0895-4356
          0895-4356
          Dec 2007
          : 60
          : 12
          Affiliations
          [1 ] Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, Geert Grooteplein 21, PO Box 9101, NL-6500 HB Nijmegen, The Netherlands. G.Borm@epid.umcn.nl
          Article
          S0895-4356(07)00061-3
          10.1016/j.jclinepi.2007.02.006
          17998077
          273223b7-a607-487f-9ad3-5d614b81d92f
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