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      Influence of Propranolol on Exercise Prescription of Training Heart Rates

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          Abstract

          Review of a longitudinal study of the effects of 40 mg of propranolol orally in 14 patients with coronary heart disease demonstrated a minor but not statistically significant change in the relationship of percentage of maximal oxygen uptake to percentage of maximal heart rate. In a cross-sectional comparison of several hundred patients who showed no other significant difference in initial findings in relation to propranolol, significant differences were present with respect to resting heart rate and responses to symptom-limited exercise, nevertheless the relationship of percentage of maximal oxygen uptake to the percentage of maximal heart rate was similar. Accordingly, we recommend maximal exercise testing in all patients prior to undertaking an exercise program so that their maximal heart rate can be determined accurately and rational training heart rates advised. The exercise test should be performed with the patients taking medications they anticipate continuing during the period of physical training, and if a change in medications is subsequently made then the exercise test should be repeated.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1980
          1980
          31 October 2008
          : 65
          : 1
          : 47-58
          Affiliations
          Division of Cardiology, University of Washington, Seattle, Wash
          Article
          170794 Cardiology 1980;65:47–58
          10.1159/000170794
          7363280
          © 1980 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 12
          Categories
          Original Paper

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