0
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found

      Calcium Flux During Hemodialysis

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          A system of equations has been derived, and examined, to describe membrane permeability and calcium fluxes within a commonly used hemodialyzer, the Mini-Kiil. By a statistical technique of sequential multiple regression analysis, factors which might influence these variables were tested on data derived from 74 hemodialysis periods in 5 patients. Calcium flux from plasma to dialysate was influenced positively by dialysate calcium concentration and plasma volume flow and negatively by dialysate volume flow. Calcium flux from dialysate to plasma was influenced positively by dialysate calcium concentration and plasma volume flow and negatively by plasma phosphate concentration. Net calcium flux from dialysate to plasma was influenced positively by the calcium gradient (dialysate calcium minus plasma ultrafiltrable calcium) and plasma volume flow and negatively by plasma phosphate concentration (coefficient of multiple correlation = 0.970). Because of the magnitude of regression coefficients, manipulations of the dialysate calcium concentration and plasma phosphate concentration were concluded to be the most practical means of adjusting calcium delivery during dialysis.

          Related collections

          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1978
          1978
          02 December 2008
          : 20
          : 3
          : 132-140
          Affiliations
          Mayo Clinic and Mayo Foundation, Rochester, Minn., and the University of Texas Health Science Center and Audie Murphy Veterans Administration Hospital, San Antonio, Tex.
          Article
          181211 Nephron 1978;20:132–140
          10.1159/000181211
          628495
          © 1978 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 9
          Categories
          Original Paper

          Cardiovascular Medicine, Nephrology

          Hemodialysis, Calcium flux, Phosphate

          Comments

          Comment on this article