In the United States, White samples are often portrayed as if their racial identities were inconsequential to their thoughts, feelings, and behaviors, and research findings derived from White samples are often portrayed as if they were generalizable to all humans. We argue that these and other practices are rooted in a “White = neutral” framework (i.e., the conceptualization of White samples as nonracial). First, we review existing data and present some new data to highlight the scope of the White = neutral framework. Second, we integrate research from across psychological science to argue that the continued use of the White = neutral framework will prevent psychology from becoming a truly objective and inclusive science for at least three reasons: (a) Research with White samples will be valued over research with samples of color, (b) norms that maintain White neutrality will remain unchallenged, and (c) the role of White identity in psychological processes will remain underspecified and underexamined. Third, we provide recommendations for how to move beyond the White = neutral framework in hopes of encouraging all psychological scientists to move toward a White ≠ neutral framework in which all samples are identified for the unique and diverse perspectives that they bring to the world.