Karina Quiaoit: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Daniel DiCenzo: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Kashuf Fatima: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– review & editing
Divya Bhardwaj: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Lakshmanan Sannachi: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Mehrdad Gangeh: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Ali Sadeghi-Naini:
ORCID: http://orcid.org/0000-0001-5055-339X
Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Archya Dasgupta: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Michael C. Kolios: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Maureen Trudeau: Role: Formal analysisRole: MethodologyRole: ResourcesRole: Writing – original draftRole:
Writing – review & editing
Sonal Gandhi: Role: Formal analysisRole: MethodologyRole: Writing – original draftRole: Writing
– review & editing
Andrea Eisen: Role: Formal analysisRole: MethodologyRole: Writing – original draftRole: Writing
– review & editing
Frances Wright: Role: Formal analysisRole: MethodologyRole: ResourcesRole: Writing – original draftRole:
Writing – review & editing
Nicole Look-Hong: Role: Formal analysisRole: MethodologyRole: Writing – original draftRole: Writing
– review & editing
Arjun Sahgal: Role: Formal analysisRole: MethodologyRole: ResourcesRole: Writing – original draftRole:
Writing – review & editing
Greg Stanisz: Role: Formal analysisRole: MethodologyRole: Writing – original draftRole: Writing
– review & editing
Christine Brezden: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Robert Dinniwell: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
William T. Tran: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Wei Yang: Role: Formal analysisRole: MethodologyRole: ResourcesRole: Writing – original draftRole:
Writing – review & editing
Belinda Curpen: Role: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Gregory J. Czarnota:
ORCID: http://orcid.org/0000-0002-0519-2182
Role: ConceptualizationRole: Formal analysisRole: Funding acquisitionRole: InvestigationRole:
MethodologyRole: ResourcesRole: SupervisionRole: Writing – original draftRole: Writing
– review & editing
Sandro Pasquali: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
27
July
2020
Publication date Collection: 2020
Volume: 15
Issue: 7
Electronic Location Identifier: e0236182
Affiliations
[1
]
Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Canada
[2
]
Department of Radiation Oncology, University of Toronto, Toronto, Canada
[3
]
Physical Sciences, Sunnybrook Research Institute, Toronto, Canada
[4
]
Department of Medical Biophysics, University of Toronto, Toronto, Canada
[5
]
Department of Electrical Engineering and Computer Sciences, Lassonde School of Engineering,
York University, Toronto, Canada
[6
]
Department of Physics, Ryerson University, Toronto, Canada
[7
]
Medical Oncology, Department of Medicine, Sunnybrook Health Sciences Centre, Toronto,
Canada
[8
]
Department of Medicine, University of Toronto, Toronto, Canada
[9
]
Surgical Oncology, Department of Surgery, Sunnybrook Health Sciences Centre, Toronto,
Canada
[10
]
Department of Surgery, University of Toronto, Toronto, Canada
[11
]
Department of Medical Oncology, Saint Michael's Hospital, University of Toronto, Toronto,
Canada
[12
]
Department of Radiation Oncology, Princess Margaret Hospital, University Health Network,
Toronto, Canada
[13
]
Department of Radiation Oncology, London Health Sciences Centre, London, Canada
[14
]
Department of Oncology, Schulich School of Medicine and Dentistry, Western University,
London, Ontario, Canada
[15
]
Evaluative Clinical Sciences, Sunnybrook Research Institute, Toronto, Canada
[16
]
Department of Diagnostic Radiology, University of Texas, M.D. Anderson Cancer Center,
Houston, Texas, United States of America
[17
]
Department of Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Canada
[18
]
Department of Medical Imaging, University of Toronto, Toronto, Canada
Fondazione IRCCS Istituto Nazionale dei Tumori, ITALY
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-20-06758
DOI: 10.1371/journal.pone.0236182
PMC ID: 7384762
PubMed ID: 32716959
SO-VID: 281e7d22-308c-4dfa-9316-c7a856db74b2
Copyright © © 2020 Quiaoit et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/501100002655, Terry Fox Foundation;
Award ID: 1083
Award Recipient
:
ORCID: http://orcid.org/0000-0002-0519-2182
Gregory J. Czarnota
Funded by: funder-id http://dx.doi.org/10.13039/501100000024, Canadian Institutes of Health Research;
Award ID: PJT 159759
Award Recipient
:
ORCID: http://orcid.org/0000-0002-0519-2182
Gregory J. Czarnota
1. Terry Fox Foundation Program Project Grant from the Hecht Foundation (grant number
1083)
https://terryfox.org 2. Canadian Institutes of Health Research (CIHR) (Grant number PJT 159759).
https://cihr-irsc.gc.ca/e/193.html. None of the funding agencies had any role in study design, data collection and analysis,
decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancer Treatment
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancers and Neoplasms
Subject:
Breast Tumors
Subject:
Breast Cancer
Subject:
Physical Sciences
Subject:
Mathematics
Subject:
Applied Mathematics
Subject:
Algorithms
Subject:
Machine Learning Algorithms
Subject:
Research and Analysis Methods
Subject:
Simulation and Modeling
Subject:
Algorithms
Subject:
Machine Learning Algorithms
Subject:
Computer and Information Sciences
Subject:
Artificial Intelligence
Subject:
Machine Learning
Subject:
Machine Learning Algorithms
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancer Treatment
Subject:
Cancer Chemotherapy
Subject:
Medicine and Health Sciences
Subject:
Pharmaceutics
Subject:
Drug Therapy
Subject:
Chemotherapy
Subject:
Cancer Chemotherapy
Subject:
Medicine and Health Sciences
Subject:
Clinical Medicine
Subject:
Clinical Oncology
Subject:
Cancer Chemotherapy
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Clinical Oncology
Subject:
Cancer Chemotherapy
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine
Subject:
Diagnostic Radiology
Subject:
Ultrasound Imaging
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
Diagnostic Radiology
Subject:
Ultrasound Imaging
Subject:
Medicine and Health Sciences
Subject:
Radiology and Imaging
Subject:
Diagnostic Radiology
Subject:
Ultrasound Imaging
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancers and Neoplasms
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
Neuroimaging
Subject:
Positron Emission Tomography
Subject:
Biology and Life Sciences
Subject:
Neuroscience
Subject:
Neuroimaging
Subject:
Positron Emission Tomography
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Positron Emission Tomography
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Positron Emission Tomography
Subject:
Medicine and Health Sciences
Subject:
Radiology and Imaging
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Positron Emission Tomography
Subject:
Medicine and Health Sciences
Subject:
Pharmaceutics
Subject:
Drug Therapy
Subject:
Chemotherapy
