Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
6
May
2016
Publication date Collection: 2016
Volume: 11
Issue: 5
Electronic Location Identifier: e0155215
Affiliations
[1
]Innovaderm Research, Montreal, Quebec, Canada
[2
]Laboratory of Investigative Dermatology, Rockefeller University, New York, New York,
United States of America
[3
]Janssen Research & Development, LLC, Spring House, Pennsylvania, United States of
America
INSERM-Université Paris-Sud, FRANCE
Author notes
Competing Interests: The authors have the following interests: This study was funded and medication provided
by Janssen Inc. Canada. Author Carrie Brodmerkel is employed by Janssen Research &
Development, LLC. Author Robert Bissonnette is employed by Innovaderm Research, Montreal.
By grants given to Rockefeller University, Centocor/Janssen has supported specific
research projects, as well as partial salary for a clinical research fellow, in his
laboratory at Rockefeller University. An investigator-initiated trial is now being
performed with ustekinumab in atopic dermatitis with funding to Rockefeller University
from Janssen. RB have been a speaker, consultant, advisory board member and investigator
and have received Honoria and grants from Janssen Inc. Abbvie, Amgen, Celgene, GSK-Steifel,
Incyte, Leo Pharma, Merck, Novartis, Tribute, Valeant, Eli-Lilly, Galderma, Xenoport,
Apopharma, Dermira, Incyte, Leo Pharma, Merck, Novartis, Pfizer, Tribute. RB is a
shareholder of of Innovaderm Research. JGK has served as a consultant to Centocor/Janssen
on matters related to the study drug (ustekinumab) and to other inflammation modulators.
The consulting has resulted in compensation of $ < 5000 per year and is thus under
the conflict of interest reporting levels as established by Rockefeller University
and the NIH. There are no patents, products in development or marketed products to
declare. This does not alter the authors' adherence to all the PLOS ONE policies on
sharing data and materials.
Conceived and designed the experiments: RB JGK. Performed the experiments: CB KMB
JFD RB XL. Analyzed the data: RB MSF CB JGK. Contributed reagents/materials/analysis
tools: RB JGK CB. Wrote the paper: RB JGK.
Article
Publisher ID:
PONE-D-15-35687
DOI: 10.1371/journal.pone.0155215
PMC ID: 4859542
PubMed ID: 27152848
SO-VID: 28c258ce-88b8-4a64-a22f-fd10779cb321
Copyright © © 2016 Bissonnette et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
This study was funded and medication provided by Janssen Inc. Canada. The funders
(Janssen Inc. Canada) had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript. Author Carrie Brodmerkel is employed
by Janssen Research & Development, LLC. Janssen Research & Development, LLC provided
support in the form of salary for author CB, but did not have any additional role
in the study design, data collection and analysis, decision to publish, or preparation
of the manuscript. The specific role of this author is articulated in the ‘author
contributions’ section. Author Robert Bissonnette is employed by Innovaderm Research,
Montreal. Innovaderm Research provided support in the form of salary for author RB,
but did not have any additional role in the study design, data collection and analysis,
decision to publish, or preparation of the manuscript. The specific role of this author
is articulated in the ‘author contributions’ section.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Clinical Medicine
Subject:
Clinical Immunology
Subject:
Autoimmune Diseases
Subject:
Psoriasis
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Clinical Immunology
Subject:
Autoimmune Diseases
Subject:
Psoriasis
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Clinical Immunology
Subject:
Autoimmune Diseases
Subject:
Psoriasis
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Research and Analysis Methods
Subject:
Bioassays and Physiological Analysis
Subject:
Microarrays
Subject:
Biology and Life Sciences
Subject:
Computational Biology
Subject:
Genome Analysis
Subject:
Transcriptome Analysis
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Genome Analysis
Subject:
Transcriptome Analysis
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Gene Mapping
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Gene Mapping
Subject:
Medicine and Health Sciences
Subject:
Surgical and Invasive Medical Procedures
Subject:
Biopsy
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Epithelial Cells
Subject:
Keratinocytes
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Epithelium
Subject:
Epithelial Cells
Subject:
Keratinocytes
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Epithelium
Subject:
Epithelial Cells
Subject:
Keratinocytes
Subject:
Research and Analysis Methods
Subject:
Mathematical and Statistical Techniques
Subject:
Statistical Methods
Subject:
Multivariate Analysis
Subject:
Principal Component Analysis
Subject:
Physical Sciences
Subject:
Mathematics
Subject:
Statistics (Mathematics)
Subject:
Statistical Methods
Subject:
Multivariate Analysis
Subject:
Principal Component Analysis
