Left ventricular ejection fraction normalization in cardiac resynchronization therapy and risk of ventricular arrhythmias and clinical outcomes: results from the Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy (MADIT-CRT) trial.

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Abstract

Appropriate guideline criteria for use of implantable cardioverter-defibrillators (ICDs) do not take into account potential recovery of left ventricular ejection fraction (LVEF) in patients treated with CRT-defibrillator.

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Author and article information

Journal

Journal ID (iso-abbrev): Circulation

Title: Circulation

ISSN (Electronic): 1524-4539

ISSN (Print): 0009-7322

Publication date (Electronic): Dec 23 2014

Volume: 130

Issue: 25

Affiliations

[1 ] From the Heart Research Follow-up Program, Division of Cardiology, University of Rochester Medical Center, Rochester, NY (M.H.R., V.K., A.-C.R., S.S., S.M., A.J.M., W.Z.); Department of Cardiology, Gentofte Hospital, Hellerup, Denmark (M.H.R., A.-C.R., C.J.); Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (S.D.S.); and Division of Cardiology, Department of Medicine, University of California, San Francisco (E.F.). mruwald@hotmail.com.

[2 ] From the Heart Research Follow-up Program, Division of Cardiology, University of Rochester Medical Center, Rochester, NY (M.H.R., V.K., A.-C.R., S.S., S.M., A.J.M., W.Z.); Department of Cardiology, Gentofte Hospital, Hellerup, Denmark (M.H.R., A.-C.R., C.J.); Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (S.D.S.); and Division of Cardiology, Department of Medicine, University of California, San Francisco (E.F.).

Article

Publisher Item ID: CIRCULATIONAHA.114.011283

DOI: 10.1161/CIRCULATIONAHA.114.011283

PubMed ID: 25301831

SO-VID: 29704bcf-9311-4481-a13a-d43df8664e3b

History

Keywords: arrhythmias, cardiac,cardiac resynchronization therapy,defibrillators, implantable,prognosis,ventricular dysfunction, left

Data availability:

Keywords: arrhythmias, cardiac, cardiac resynchronization therapy, defibrillators, implantable, prognosis, ventricular dysfunction, left

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