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      An observational study of vitamin b12 levels and peripheral neuropathy profile in patients of diabetes mellitus on metformin therapy.

      1 , 2 , 3
      Diabetes & metabolic syndrome
      Elsevier BV
      Diabetic neuropathy, Metformin, NCV, TCSS, Vitamin B12

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          Abstract

          A descriptive, observational study was completed in a tertiary care hospital between November 2014 and March 2016. Fifty consecutive patients of Type 2-Diabetes Mellitus who had been on metformin therapy for at least three months were included in our study. Several Parameters were compared with vitamin B12 levels and severity of peripheral neuropathy (using Toronto Clinical Scoring System (TCSS) and Nerve Conduction Velocity). These included the duration of diabetes, duration of metformin usage, dietary history, and HbA1c levels. Definite B12 deficiency was defined as B12<150pg/ml and possible B12 deficiency as <220pg/ml.

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          Author and article information

          Journal
          Diabetes Metab Syndr
          Diabetes & metabolic syndrome
          Elsevier BV
          1878-0334
          1871-4021
          September 9 2017
          : 12
          : 1
          Affiliations
          [1 ] Department of Medicine, Lady Hardinge Medical College, Shaheed Bhagat Singh Road, Diz Area, Connaught Place, New Delhi, 110001, India. Electronic address: kameshg9@gmail.co.
          [2 ] Department of Medicine, Lady Hardinge Medical College, Shaheed Bhagat Singh Road, Diz Area, Connaught Place, New Delhi, 110001, India. Electronic address: anandjz@gmail.com.
          [3 ] Department of Medicine, Lady Hardinge Medical College, Shaheed Bhagat Singh Road, Diz Area, Connaught Place, New Delhi, 110001, India. Electronic address: anurogi@yahoo.co.in.
          Article
          S1871-4021(17)30287-4
          10.1016/j.dsx.2017.08.014
          28882470
          29999b6b-0cbf-47fc-a4bf-a91197739cc2
          History

          TCSS,Vitamin B12,Diabetic neuropathy,Metformin,NCV
          TCSS, Vitamin B12, Diabetic neuropathy, Metformin, NCV

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