Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date Collection: 2016
Publication date
(Electronic):
24
May
2016
Volume: 11
Issue: 5
Electronic Location Identifier: e0156132
Affiliations
[1
]Department of Bioinformatics and Computational Biology, Genentech Inc., South San
Francisco, CA, United States of America
[2
]Department of Molecular Biology, Genentech Inc., South San Francisco, CA, United States
of America
University of California, Los Angeles, UNITED STATES
Author notes
Competing Interests: The authors of this manuscript have read the journal’s policy and have the following
competing interests: All authors are or have been employees of Genentech Inc. and
some hold shares in Roche. RG is an employee of 23AndMe Inc. This does not alter the
authors’ adherence to PLOS ONE policies on sharing data and materials.
Conceived and designed the experiments: LDG RG. Analyzed the data: LDG RG. Wrote the
paper: LDG RG. Provided advice on method and software development: GP ML TDW. Performed
RT-PCR experiments: YC. Provided advice and oversaw sequencing experiments: SS.
[¤]
Current address: 23andMe Inc., Mountain View, CA, United States of America
Article
Publisher ID:
PONE-D-15-21817
DOI: 10.1371/journal.pone.0156132
PMC ID: 4878813
PubMed ID: 27218464
SO-VID: 29be6d6e-c655-4cc2-9dcc-c20cc037d0ae
Copyright © © 2016 Goldstein et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
The study was funded by Genentech Inc. The funders had no role in study design, data
collection and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Gene Mapping
Subject:
Exon Mapping
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Gene Mapping
Subject:
Exon Mapping
Subject:
Computer and Information Sciences
Subject:
Data Visualization
Subject:
Infographics
Subject:
Graphs
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Artificial Gene Amplification and Extension
Subject:
Polymerase Chain Reaction
Subject:
Reverse Transcriptase-Polymerase Chain Reaction
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Artificial Gene Amplification and Extension
Subject:
Polymerase Chain Reaction
Subject:
Reverse Transcriptase-Polymerase Chain Reaction
Subject:
Research and Analysis Methods
Subject:
Simulation and Modeling
Subject:
Biology and life sciences
Subject:
Molecular biology
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
RNA sequencing
Subject:
Research and analysis methods
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
RNA sequencing
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Protein Domains
Subject:
Biology and Life Sciences
Subject:
Computational Biology
Subject:
Genome Complexity
Subject:
Introns
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Genome Complexity
Subject:
Introns
Subject:
Computer and Information Sciences
Subject:
Computer Software