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      Scholarly publishing and journal targeting in the time of the Coronavirus Disease 2019 (COVID-19) pandemic: a cross-sectional survey of rheumatologists and other specialists

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          Abstract

          The evolving research landscape in the time of the Coronavirus disease 2019 (COVID-19) pandemic calls for greater understanding of the perceptions of scholars regarding the current state and future of publishing. An anonymised and validated e-survey featuring 30 questions was circulated among rheumatologists and other specialists over social media to understand preferences while choosing target journals, publishing standards, commercial editing services, preprint archiving, social media and alternative publication activities. Of 108 respondents, a significant proportion were clinicians (68%), researchers (60%) and educators (47%), with median 23 publications and 15 peer-review accomplishments. The respondents were mainly rheumatologists from India, Ukraine and Turkey. While choosing target journals, relevance to their field (69%), PubMed Central archiving (61%) and free publishing (59%) were the major factors. Thirty-nine surveyees (36%) claimed that they often targeted local journals for publishing their research. However, only 18 (17%) perceived their local society journals as trustworthy. Occasional publication in the so-called predatory journals (5, 5%) was reported and obtaining support from commercial editing agencies to improve English and data presentation was not uncommon (23, 21%). The opinion on preprint archiving was disputed; only one-third believed preprints were useful. High-quality peer review (56%), full and immediate open access (46%) and post-publication social media promotion (32%) were identified as key anticipated features of scholarly publishing in the foreseeable future. These perceptions of surveyed scholars call for greater access to free publishing, attention to proper usage of English and editing skills, and a larger role for engagement over social media.

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          Information and Misinformation on COVID-19: a Cross-Sectional Survey Study

          Background The coronavirus disease 2019 (COVID-19) pandemic has led to a large volume of publications, a barrage of non-reviewed preprints on various professional repositories and a slew of retractions in a short amount of time. Methods We conducted an e-survey using a cloud-based website to gauge the potential sources of trustworthy information and misinformation and analyzed researchers', clinicians', and academics' attitude toward unpublished items, and pre- and post-publication quality checks in this challenging time. Results Among 128 respondents (mean age, 43.2 years; M:F, 1.1:1), 60 (46.9%) were scholarly journal editors and editorial board members. Social media channels were distinguished as the most important sources of information as well as misinformation (81 [63.3%] and 86 [67.2%]). Nearly two in five (62, 48.4%) respondents blamed reviewers, editors, and misinterpretation by readers as additional contributors alongside authors for misinformation. A higher risk of plagiarism was perceived by the majority (70, 58.6%), especially plagiarism of ideas (64.1%) followed by inappropriate paraphrasing (54.7%). Opinion was divided on the utility of preprints for changing practice and changing retraction rates during the pandemic period, and higher rejections were not supported by most (76.6%) while the importance of peer review was agreed upon by a majority (80, 62.5%). More stringent screening by journal editors (61.7%), and facilitating open access plagiarism software (59.4%), including Artificial Intelligence (AI)-based algorithms (43.8%) were among the suggested solutions. Most (74.2%) supported the need to launch a specialist bibliographic database for COVID-19, with information indexed (62.3%), available as open-access (82.8%), after expanding search terms (52.3%) and following due verification by academics (66.4%), and journal editors (52.3%). Conclusion While identifying social media as a potential source of misinformation on COVID-19, and a perceived high risk of plagiarism, more stringent peer review and skilled post-publication promotion are advisable. Journal editors should play a more active role in streamlining publication and promotion of trustworthy information on COVID-19.
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            Rheumatologists’ perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets

            The ongoing pandemic coronavirus disease 19 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a matter of global concern. Environmental factors such as air pollution and smoking and comorbid conditions (hypertension, diabetes mellitus and underlying cardio-respiratory illness) likely increase the severity of COVID-19. Rheumatic manifestations such as arthralgias and arthritis may be prevalent in about a seventh of individuals. COVID-19 can result in acute interstitial pneumonia, myocarditis, leucopenia (with lymphopenia) and thrombocytopenia, also seen in rheumatic diseases like lupus and Sjogren’s syndrome. Severe disease in a subset of patients may be driven by cytokine storm, possibly due to secondary hemophagocytic lymphohistiocytosis (HLH), akin to that in systemic onset juvenile idiopathic arthritis or adult-onset Still’s disease. In the absence of high-quality evidence in this emerging disease, understanding of pathogenesis may help postulate potential therapies. Angiotensin converting enzyme 2 (ACE2) appears important for viral entry into pneumocytes; dysbalance in ACE2 as caused by ACE inhibitors or ibuprofen may predispose to severe disease. Preliminary evidence suggests potential benefit with chloroquine or hydroxychloroquine. Antiviral drugs like lopinavir/ritonavir, favipiravir and remdesivir are also being explored. Cytokine storm and secondary HLH might require heightened immunosuppressive regimens. Current international society recommendations suggest that patients with rheumatic diseases on immunosuppressive therapy should not stop glucocorticoids during COVID-19 infection, although minimum possible doses may be used. Disease-modifying drugs should be continued; cessation may be considered during infection episodes as per standard practices. Development of a vaccine may be the only effective long-term protection against this disease. Key Points • Patients with coronavirus disease 19 (COVID-19) may have features mimicking rheumatic diseases, such as arthralgias, acute interstitial pneumonia, myocarditis, leucopenia, lymphopenia, thrombocytopenia and cytokine storm with features akin to secondary hemophagocytic lymphohistiocytosis. • Although preliminary results may be encouraging, high-quality clinical trials are needed to better understand the role of drugs commonly used in rheumatology like hydroxychloroquine and tocilizumab in COVID-19. • Until further evidence emerges, it may be cautiously recommended to continue glucocorticoids and other disease-modifying antirheumatic drugs (DMARDs) in patients receiving these therapies, with discontinuation of DMARDs during infections as per standard practice.
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              Retracted COVID-19 articles: a side-effect of the hot race to publication

              Dear Editor: In early 2020, coronavirus disease 2019 (COVID-19) caused a pandemic, affecting the entire globe. Initially, the disease was relatively unknown. However, as COVID-19 became more widespread, our knowledge regarding the virus and its resultant disease increased. The healthcare system and policymakers in different countries relied on articles published on the subject, from epidemiological features to useful drugs and at-risk populations, for their decisions. Thousands of research articles have since been published on COVID-19 and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Researchers were and are keen to publish their COVID-19-related research as quickly as possible in this hot race to publication. In this atmosphere, the accuracy and quality of published articles might cause some concerns. Although pre-publication peer-review systems are undeniably robust and traditionally employed in scientific publications, post-publication review is flourishing during this pandemic era. Researchers and scholars have critically scrutinized the COVID-19-related scientific output of medical journals, leading to several corrections and retractions. Moreover, some authors later noticed some inconsistencies in their published work, which forced them to withdraw their articles. Through this letter, the authors aimed to show an evaluation of the retracted COVID-19 articles. The database of retraction watch was searched on June 18, 2020, using “COVID-19”, “coronavirus disease 2019”, “coronavirus 2019”, “SARS-COV-2”, and “2019-nCov” as keywords. Additionally, the special webpage in retraction watch was analyzed for retracted or withdrawn articles (Marcus 2020). The search retrieved a total of 26 articles from the retraction watch database. Of these articles, two were temporarily retracted (Cai et al. 2020; Yin 2020), two received an expression of concern (Gautret et al. 2020; Wang et al. 2020a, b), and two have been currently corrected (Sriwijitalai and Wiwanitkit 2020; Tang et al. 2020). One was a withdrawn preprint as it was submitted to the preprint server without the full consent of all the authors. This preprint is now published in the Cell Host and Microbes journal (Chen et al. 2020). Moreover, a reliable access was not obtained to one article titled “Corona Virus Killed by Sound Vibrations Produced by Thali or Ghanti: A Potential Hypothesis” mentioned in the special COVID-19 webpage in retraction watch. Finally, one preprint shown in the retraction watch search was resubmitted without explanation (Daneshkhah et al. 2020). The characteristics of the remaining seventeen articles are discussed below (Pradhan et al. 2020; Yang et al. 2020; Wang et al. 2020a, b; Bae et al. 2020; Parves 2020; Chu et al. 2020; Mehra et al. 2020a, b; Karami et al. 2020; Davido et al. 2020; Nouvier et al. 2020; Gormley and Ngan 2020; Zhuang et al. 2020; Siyu et al. 2020; Zeng and Zhen 2020; Luo et al. 2020; Tofade and Daftary 2020). Among the seventeen articles involved in this analysis, six were preprints (and thus article type was not assigned), five were research articles, two were letters, two were case reports, and two were sorts of commentaries. The countries with the highest numbers of retracted or withdrawn articles were China with seven articles, followed by the United States with six articles (Fig. 1). Reasons for retraction or withdrawal were searched both in the journal websites and in the retraction watch database. According to this search, the most common reasons for retraction were concerns, issues, and errors in results and/or conclusions, followed by concerns, issues, and errors in data (Table 1). Fig. 1 Number of retracted/withdrawn COVID-19 articles from different countries Table 1 Reasons for retraction/withdrawal of COVID-19 articles Reason for retraction or withdrawal Number of cases Concerns, issues, or errors in results and/or conclusions 8 Concerns, issues, or errors in data 7 Duplication due to error of the journal/publisher 2 Duplication due to report of the case by another team 1 Error in analysis 1 Copyright claims 1 Ethical violation by the author 1 Lack of approval from a third party 1 Concerns/issues about third party involvement 1 Investigation by a third party 1 Concerns/issues about authorship (dishonest presentation) 1 Not mentioned 2 Some of these retractions even drew the attention of news outlets and have been widely discussed among the public. The most prominent examples are the retraction of articles from The Lancet and The New England Journal of Medicine. The Lancet article reported that increased in-hospital mortality was associated with hydroxychloroquine or chloroquine, while The New England Journal of Medicine article did not confirm the association of angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers with in-hospital deaths in COVID-19 patients (Hopkins and Gold 2020; Davey 2020). However, both articles were retracted after a further post-publication review. Another interesting case was a letter submitted to The Lancet Global Health describing the situation of nurses in Wuhan, China, allegedly in a first-person narrative. However, the authors later informed the journal that the experience described in the letter was not a first-hand account. In another incident, the authors of a case report on the first COVID-19-related mortality in pregnant women, withdrew the report when they were notified that another team in a different hospital had submitted and published the same report. In two separate instances, a journal made the mistake of duplicate publication of an article. In general, it seems the main reason underlying these retractions and withdrawals is the rush to quickly publish the COVID-19-related articles, whether by the authors or the journal editors and review teams. The publishing parties must keep in mind that swiftly published but erroneous data is not helpful for the medical community in their ongoing battle with COVID-19. What we actually need (possibly more than any time) is correct, meticulous, and unbiased information passed through rigorous critical appraisal methods of the scientific community.
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                Author and article information

                Contributors
                durgapmisra@gmail.com
                Journal
                Rheumatol Int
                Rheumatol Int
                Rheumatology International
                Springer Berlin Heidelberg (Berlin/Heidelberg )
                0172-8172
                1437-160X
                13 October 2020
                : 1-8
                Affiliations
                [1 ]GRID grid.263138.d, ISNI 0000 0000 9346 7267, Department of Clinical Immunology and Rheumatology, , Sanjay Gandhi Postgraduate Institute of Medical Sciences, ; Lucknow, India
                [2 ]GRID grid.416281.8, ISNI 0000 0004 0399 9948, Departments of Rheumatology and Research and Development, , Dudley Group NHS Foundation Trust (Teaching Trust of the University of Birmingham, UK), Russells Hall Hospital, ; Dudley, West Midlands UK
                [3 ]GRID grid.411517.7, ISNI 0000 0004 0563 0685, Department of Internal Medicine No. 2, , Danylo Halytsky Lviv National Medical University, ; Lviv, Ukraine
                Author information
                http://orcid.org/0000-0003-2753-2990
                http://orcid.org/0000-0001-8749-6018
                http://orcid.org/0000-0002-4188-8486
                http://orcid.org/0000-0002-5035-7396
                Article
                4718
                10.1007/s00296-020-04718-x
                7552576
                33048199
                29e83d5e-2d44-4f62-aa55-46d234f25b48
                © Springer-Verlag GmbH Germany, part of Springer Nature 2020

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

                History
                : 18 September 2020
                : 28 September 2020
                Categories
                Observational Research

                Rheumatology
                covid-19,rheumatology,open access publishing,social media,archiving,preprints,periodicals as topic

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