- Record: found
- Abstract: found
- Article: not found
Genetic linkage of the Marfan syndrome, ectopia lentis, and congenital contractural arachnodactyly to the fibrillin genes on chromosomes 15 and 5. The International Marfan Syndrome Collaborative Study.
P Tsipouras
1 ,
R Del Mastro ,
M Sarfarazi ,
B Lee ,
E Vitale ,
A H Child ,
M Godfrey ,
R B Devereux ,
D Hewett ,
B Steinmann
Apr 2 1992
Read this article at
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
The large glycoprotein fibrillin is a structural component of elastin-containing microfibrils found in many tissues. The Marfan syndrome has been linked to the fibrillin gene on chromosome 15, but congenital contractural arachnodactyly, which shares some of the physical features of the syndrome, has been linked to the fibrillin gene on chromosome 5.