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      Acute esophageal necrosis: A rare case of upper gastrointestinal bleeding from diabetic ketoacidosis

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          Abstract

          Acute esophageal necrosis, also known as black esophagus or acute necrotizing esophagitis is a rare condition with roughly 154 cases reported in the literature. This condition is classically diagnosed on its endoscopic findings of a circumferentially black esophagus that abruptly ends at the gastroesophageal junction and transitions to normal gastric mucosa. When present, acute esophageal necrosis potentially signifies a poor prognosis with an overall mortality up to 36%. This case report describes a critically ill patient with multiple comorbidities that was found to have acute esophageal necrosis the entire length of the esophagus secondary to ischemia/hypoperfusion that was caused by diabetic ketoacidosis. The patient had a prolonged hospitalization but was ultimately discharged in stable condition. We also review the literature of this rare esophageal condition.

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          Clinical presentations, management, and outcomes of acute esophageal necrosis: a systemic review.

          To review all the reported literature on acute esophageal necrosis.
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            Acute esophageal necrosis: a case report and review

            Acute esophageal necrosis, commonly referred to as “black esophagus” or “acute necrotizing esophagitis”, is a rare clinical disorder with an unclear etiology. The definition excludes patients with a history of recent caustic ingestion. Oesophageal necrosis can be diagnosed at endoscopy by the presence of black necroting appearing oesophagus. Contrary to the caustic oesophagitis whose treatment is often surgical, treatment of the acute necrositing oesophagitis is primarily medical. The prognosis for patients who develop acute necrotizing oesophagitis is generally poor. We report a new case of acute necrotizing oesophagitis and undertook a literature review of this rare diagnosis.
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              An Unusual Cause of Acute Upper Gastrointestinal Bleeding: Acute Esophageal Necrosis

              Acute esophageal necrosis (AEN), also called “black esophagus,” is a condition characterized by circumferential necrosis of the esophagus with universal distal involvement and variable proximal extension with clear demarcation at the gastroesophageal junction. It is an unusual cause of upper gastrointestinal bleeding and is recognized with distinct and striking mucosal findings on endoscopy. The patients are usually older and are critically ill with shared comorbidities, which include atherosclerotic cardiovascular disease, diabetes mellitus, hypertension, chronic renal insufficiency, and malnutrition. Alcoholism and substance abuse could be seen in younger patients. Patients usually have systemic hypotension along with upper abdominal pain in the background of clinical presentation of hematemesis and melena. The endoscopic findings confirm the diagnosis and biopsy is not always necessary unless clinically indicated in atypical presentations. Herein we present two cases with distinct clinical presentation and discuss the endoscopic findings along with a review of the published literature on the management of AEN.
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                Author and article information

                Journal
                Clin Pract
                CP
                Clinics and Practice
                PAGEPress Publications, Pavia, Italy
                2039-7275
                2039-7283
                29 June 2020
                19 May 2020
                : 10
                : 2
                : 1254
                Affiliations
                [1 ]Department of Internal Medicine
                [2 ]Department of Gastroenterology and Hepatology, MercyOne Des Moines Medical Center, Des Moines , IA, USA
                Author notes
                MercyOne Des Moines Medical Center, 1111 6th Avenue, Des Moines, IA 50314 USA. +1.(515).643-2261 - +1.(515).643-5802 duhlenhopp@ 123456mercydesmoines.org

                Contributions: Each author contributed substantially to the work, worked on the drafting or revising of the manuscript, and were involved in its final approval.

                Conflict of interest: the authors declare no potential conflict of interests.

                Ethical approval: Our institution does not require ethical approval for reporting individual cases or case series.

                Consent: Informed consent was obtained from the patient for anonymized information to be published in this article. A completed consent form can be made available to the journal Editor if specifically requested.

                Article
                10.4081/cp.2020.1254
                7348660
                32670536
                2a484991-ca65-4829-b4a9-b989697338c4
                ©Copyright: the Author(s)

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 30 March 2020
                : 12 June 2020
                Page count
                Figures: 1, Tables: 0, Equations: 0, References: 9, Pages: 2
                Categories
                Case Report

                acute esophageal necrosis,black esophagus,acute necrotizing esophagitis,diabetic ketoacidosis,upper gastrointestinal bleed

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