Effect of chemical environment changes in cell on DNA structures and functions

Abstract

Diseases are caused by mutations in DNA sequences. DNA tends to form double-helix structures but in more recent times, it has been found that it can also form non-canonical structures in response to changes in the environment around it. Japanese researchers have now unearthed some exciting findings about the chain reaction that results, potentially leading to diseases such as cancer. Associate Professor Hisae Tateishi-Karimata and Professor Naoki Sugimoto are based at the Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University in Japan, and are collaborating on important work to better understand the complex inner workings of cells in disease. An area of focus for this research is the elucidation of mechanisms of diseases caused by non-canonical structures of DNA and regulation for DNA function.

Journal

Title: Impact

Abbreviated Title: impact

Publisher: Science Impact, Ltd.

ISSN (Print): 2398-7073

Publication date Created: November 30 2020

Publication date (Print): November 30 2020

Volume: 2020

Issue: 7

Pages: 25-27

Article

DOI: 10.21820/23987073.2020.7.25

SO-VID: 2a66a5af-19fc-4735-8525-094122bae3c0

Copyright statement: © 2020

License:

This work is licensed under a Creative Commons Attribution 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

Product

Self URI (article page): https://www.ingentaconnect.com/content/10.21820/23987073.2020.7.25