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      Can stone density on plain radiography predict the outcome of extracorporeal shockwave lithotripsy for ureteral stones?

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          Abstract

          Purpose

          The objective was to determine whether stone density on plain radiography (kidney-ureter-bladder, KUB) could predict the outcome of extracorporeal shockwave lithotripsy (ESWL) for ureteral stones.

          Materials and Methods

          A total of 223 patients treated by ESWL for radio-opaque ureteral stones of 5 to 20 mm were included in this retrospective study. All patients underwent routine blood and urine analyses, plain radiography (KUB), and noncontrast computed tomography (NCCT) before ESWL. Demographic, stone, and radiological characteristics on KUB and NCCT were analyzed. The patients were categorized into two groups: lower-density (LD) group (radiodensity less than or equal to that of the 12th rib, n=163) and higher-density (HD) group (radiodensity greater than that of the 12th rib, n=60). Stone-free status was assessed by KUB every week after ESWL. A successful outcome was defined as stone free within 1 month after ESWL.

          Results

          Mean stone size in the LD group was significantly smaller than that in the HD group (7.5±1.4 mm compared with 9.9±2.9 mm, p=0.002). The overall success rates in the LD and HD groups were 82.1% and 60.0%, respectively (p=0.007). The mean duration of stone-free status and average number of SWL sessions required for success in the two groups were 21.7 compared with 39.2 days and 1.8 compared with 2.3, respectively (p<0.05). On multivariate logistic analysis, stone size and time to ESWL since colic and radiodensity of the stone on KUB were independent predictors of successful ESWL.

          Conclusions

          Our data suggest that larger stone size, longer time to ESWL, and ureteral stones with a radiodensity greater than that of the 12th rib may be at a relatively higher risk of ESWL failure 1 month after the procedure.

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          Most cited references20

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          2007 Guideline for the management of ureteral calculi.

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            Shock wave lithotripsy success determined by skin-to-stone distance on computed tomography.

            To evaluate whether the skin-to-stone distance (SSD), body mass index (BMI), and Hounsfield unit (HU) density can be used as independent predictors of stone-free (SF) status after shock wave lithotripsy (SWL) of lower pole kidney stones. No studies have evaluated the SSD by non-contrast-enhanced computed tomography (NCCT) as a predictor of SWL success. Studies have suggested that the BMI and HU density of urinary calculi on NCCT may predict the SF rate after SWL. The radiographs of 64 patients treated with SWL (DoliS lithotripter) from March 2000 to April 2004 with lower pole kidney stones measuring 0.5 to 1.5 cm on NCCT were reviewed. The average SSD was calculated by measuring three distances from the center of the stone to the skin (0 degrees, 45 degrees, and 90 degrees angles) on NCCT. The BMI and HU density were determined, and chemical analysis was performed on all stones. Radiographic assessment of the kidneys, ureter, and bladder at 6 weeks categorized patients into the SF or residual stone group. Logistic regression was fit, using SSD, BMI, and HU density as predictors, to assess the SF rates after SWL. Of 64 patients, 30 were SF and 34 had residual stones. The mean SSD was 8.12 +/- 1.74 cm for the SF group versus 11.53 +/- 1.89 cm for the residual stone group (P <0.01). Logistic regression analysis revealed only SSD to be a significant predictor of outcome (odds ratio 0.32, 95% confidence interval 0.29 to 0.35, P <0.01). An SSD greater than 10 cm predicted treatment failure. The SSD may predict the outcome after SWL of lower pole kidney stones. SWL in patients with an SSD greater than 10 cm is likely to fail. The use of the SSD may be transferable to the treatment of all urinary stones, regardless of location.
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              Guidelines on urolithiasis.

              A project was initiated by the Health Care Office of the European Association of Urology in order to formulate common recommendations and guidelines for the treatment of patients with urolithiasis. The basic task for the working group therefore was to extract and evaluate evidence from the literature in order to reach a consensus on how these patients could best be managed. Extensive reviews of the literature together with a thorough and detailed discussion of the various topics, by a working group including of experts from several European countries, provided the basis for a consensus overview of urolithiasis and its management. Recommendations are given for the management of patients with acute stone colic and for active removal of stones from the ureter and kidney. Moreover, the principles for risk evaluation of patients with recurrent stone formation and appropriate recurrence preventive treatment are given.
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                Author and article information

                Journal
                Korean J Urol
                Korean J Urol
                KJU
                Korean Journal of Urology
                The Korean Urological Association
                2005-6737
                2005-6745
                January 2015
                06 January 2015
                : 56
                : 1
                : 56-62
                Affiliations
                Department of Urology, Dongguk University Ilsan Hospital, Goyang, Korea.
                [1 ]Department of Radiology, Dongguk University Ilsan Hospital, Goyang, Korea.
                Author notes
                Corresponding Author: Hae Won Lee. Department of Urology, Dongguk University Ilsan Hospital, 27 Dongguk-ro, Ilsandong-gu, Goyang 410-773, Korea. TEL: +82-31-961-7453, FAX: +82-31-961-7457, urmarine@ 123456dumc.or.kr
                Article
                10.4111/kju.2015.56.1.56
                4294856
                25598937
                2a80eba6-21a2-4494-a670-169acd197a0f
                © The Korean Urological Association, 2015

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 05 September 2014
                : 27 October 2014
                Funding
                Funded by: Dongguk University
                Categories
                Original Article
                Endourology/Urolithiasis

                Urology
                bone density,lithotripsy,ureteral calculi
                Urology
                bone density, lithotripsy, ureteral calculi

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