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Conditionally replicating adenovirus therapy utilizing bone sialoprotein promoter (Ad-BSP-E1a) in an in vivo study of treating androgen-independent intraosseous prostate cancer
November 2011
November 2011
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Abstract
Adenoviral based gene therapy has been used in clinical trials in control of advanced
prostate cancer. In this study, a promising conditionally replicating adenovirus (CRAd)
driven by a tissue specific bone sialoprotein promoter in controlling prostate cancer
both in vitro and in vivo is demonstrated.