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Murine gammaherpesvirus 68: a model for the study of gammaherpesvirus pathogenesis
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Abstract
Murine gammaherpesvirus 68 (MHV-68) is a naturally occurring herpesvirus of wild rodents
and is genetically related to human herpesvirus 8 and Epstein-Barr virus. The ability
of MHV-68 to establish acute and persistent infection within laboratory mice offers
a unique opportunity to investigate immunological and virological aspects of gammaherpesvirus
pathogenesis.