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      Tissue pulsatility imaging of cerebral vasoreactivity during hyperventilation.

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          Abstract

          Tissue pulsatility imaging (TPI) is an ultrasonic technique that is being developed at the University of Washington to measure tissue displacement or strain as a result of blood flow over the cardiac and respiratory cycles. This technique is based in principle on plethysmography, an older nonultrasound technology for measuring expansion of a whole limb or body part due to perfusion. TPI adapts tissue Doppler signal processing methods to measure the "plethysmographic" signal from hundreds or thousands of sample volumes in an ultrasound image plane. This paper presents a feasibility study to determine if TPI can be used to assess cerebral vasoreactivity. Ultrasound data were collected transcranially through the temporal acoustic window from four subjects before, during and after voluntary hyperventilation. In each subject, decreases in tissue pulsatility during hyperventilation were observed that were statistically correlated with the subject's end-tidal CO2 measurements. (

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          Author and article information

          Journal
          Ultrasound Med Biol
          Ultrasound in medicine & biology
          Elsevier BV
          0301-5629
          0301-5629
          Aug 2008
          : 34
          : 8
          Affiliations
          [1 ] Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, Seattle, WA, USA. kucewicz@u.washington.edu
          Article
          S0301-5629(08)00005-7 NIHMS64273
          10.1016/j.ultrasmedbio.2008.01.001
          2582389
          18336991
          2ad0e302-79a6-449d-8dcd-0dd6ebc1c2ca
          History

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