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      Vascular endothelial growth factor, left ventricular dysfunction and mortality in hemodialysis patients.

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          Abstract

          Vascular endothelial growth factor induces nitric oxide-dependent angiogenic effects and participates in the inflammatory response. This cytokine is over-expressed in the myocardium in experimental models of pressure overload and renal mass ablation, and vascular endothelial growth factor is increased in end-stage renal disease. We investigated the relationship between vascular endothelial growth factor, left ventricular function (by midwall fractional shortening) and mortality in a prospective cohort study in 228 hemodialysis patients.

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          Author and article information

          Journal
          J. Hypertens.
          Journal of hypertension
          Ovid Technologies (Wolters Kluwer Health)
          0263-6352
          0263-6352
          Sep 2008
          : 26
          : 9
          Affiliations
          [1 ] CNR-IBIM, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Disease and Hypertension, Reggio Calabria, Italy.
          Article
          00004872-200809000-00023
          10.1097/HJH.0b013e328307c3d2
          18698224

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