Lack of Effect of Acute Prolactin Suppression on Renal Water, Sodium and Potassium Excretion during Sleep

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Abstract

The possible role of endogenous prolactin (hPRL) in the regulation of renal water, Na and K excretion during sleep was tested in a group of 10 healthy female volunteers. Plasma hPRL and total urinary Na and K excretion were measured at 2- and 4-hourly intervals, respectively, in the control period and after prolactin inhibition with bromocriptin. Despite adequate prolactin suppression, no significant changes were observed in the nyctohemeral excretion rhythms of water, Na and K, suggesting that endogenous prolactin is not instrumental in the control of these parameters.

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Journal ID (publisher-id): HRE

Journal ID (nlm-ta): Horm Res Paediatr

Journal ID (doi): 10.1159/issn.1663-2818

Title: Hormone Research in Paediatrics

Publisher: S. Karger AG

ISSN (Print): 1663-2818

ISSN (Electronic): 1663-2826

Publication date Subscription-year: 1976

Publication date (Print): 1976

Publication date (Electronic): 21 November 2008

Volume: 7

Issue: 1

Pages: 11-15

Affiliations

Experimental Therapeutics Department, Biological and Medical Research Division, Sandoz Ltd., Basle, and University Medical Clinic, Inselspital, Berne

Article

Publisher ID: 178703 Other ID: Horm Res 1976;7:11–15

DOI: 10.1159/000178703

PubMed ID: 1036731

SO-VID: 2b6263ee-287f-41f0-a4d6-df9625df4c20

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Lack of Effect of Acute Prolactin Suppression on Renal Water, Sodium and Potassium Excretion during Sleep

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Karger: Endocrinology

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