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      Lack of Effect of Acute Prolactin Suppression on Renal Water, Sodium and Potassium Excretion during Sleep


      Hormone Research in Paediatrics

      S. Karger AG

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          The possible role of endogenous prolactin (hPRL) in the regulation of renal water, Na and K excretion during sleep was tested in a group of 10 healthy female volunteers. Plasma hPRL and total urinary Na and K excretion were measured at 2- and 4-hourly intervals, respectively, in the control period and after prolactin inhibition with bromocriptin. Despite adequate prolactin suppression, no significant changes were observed in the nyctohemeral excretion rhythms of water, Na and K, suggesting that endogenous prolactin is not instrumental in the control of these parameters.

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          Horm Res Paediatr
          Hormone Research in Paediatrics
          S. Karger AG
          21 November 2008
          : 7
          : 1
          : 11-15
          Experimental Therapeutics Department, Biological and Medical Research Division, Sandoz Ltd., Basle, and University Medical Clinic, Inselspital, Berne
          178703 Horm Res 1976;7:11–15
          © 1976 S. Karger AG, Basel

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          Pages: 5


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