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      Thermodynamic and fluorescence analyses to determine mechanisms of IgG1 stabilization and destabilization by arginine.

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          Abstract

          To investigate mechanisms governing the stabilization and destabilization of immunoglobulin (IgG1) by arginine (Arg).

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          Author and article information

          Journal
          Pharm. Res.
          Pharmaceutical research
          Springer Nature America, Inc
          1573-904X
          0724-8741
          Apr 2014
          : 31
          : 4
          Affiliations
          [1 ] Product Engineering Department, Chugai Pharmaceutical Co., Ltd., 5-5-1 Ukima, Kita-ku, Tokyo, 115-8543, Japan, fukuda.masakazu76@chugai-pharm.co.jp.
          Article
          10.1007/s11095-013-1221-2
          24287623
          2b838fa3-d7f7-4d69-9807-e00190566b6f
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