The effect of single periocular injection of methylprednisolone and drainage of suprachoroidal fluid in the treatment of rhegmatogenous retinal detachment combined with choroidal detachment
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Abstract
In this study we compared the anatomic and functional outcomes of two steroid treatments
on rhegmatogenous retinal detachment (RRD) combined with choroidal detachment (CD),
namely treatment with oral prednisolone (1 mg/kg daily) for 3–7 days before vitrectomy
or a single periocular injection of methylprednisolone (40 mg) 1–3 days before vitrectomy.
We also analyzed the outcomes of the eyes with subsided CD and the eyes with persistent
CD that underwent drainage of suprachoroidal fluids during the vitrectomy. This was
a prospective randomized study. Seventy five eyes with RRD combined with CD were divided
into 2 groups based on the two different treatment regimens as above. The eyes in
each group were further divided into 2 subgroups (A: CD subsided eyes; B: CD persistent
eyes) according to the response of CD to the treatment of steroids. Retinal reattachment
rates were measured at 6 months after the removal of silicone oil. At 6 months after
silicone oil removal, the retinal reattachment rate was similar ( p = 0.666) in the
oral prednisolone group (91.7%, 33/36) and the periocular injection group (94.9%,
37/39). Similar retinal reattachment rates ( p = 0.364) were also found in the CD
subsided eyes (97.1%, 34/35) and the CD persistent eyes (90.0%, 36/40). The retinal
reattachment rate was comparable among the subgroups ( p = 0.395; oral prednisolone
A group: 95.2%, 20/21; oral prednisolone B group: 86.7%, 13/15; periocular injection
A group: 100%, 14/14; periocular injection B group: 92.0%, 23/25). For RRD combined
with CD, eyes treated with a single periocular injection of methylprednisolone (40 mg,
1–3 days before pars plana vitrectomy) combined with the drainage of suprachoroidal
fluids during the surgery had similar anatomic and functional outcomes compared to
the eyes treated with oral prednisolone for 3–7 days before vitrectomy.
To investigate the characteristics of rhegmatogenous retinal detachment associated with choroidal detachment (RRDCD) in a Chinese population by using ultrasound biomicroscope (UBM).