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      Renal, efficacy and safety outcomes following late conversion of kidney transplant patients from calcineurin inhibitor therapy to everolimus: the randomized APOLLO study.

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          Abstract

          The primary objective of this trial was to demonstrate, based on the estimated glomerular filtration rate (eGFR), superior renal function at month 12 after conversion of maintenance kidney transplant patients from calcineurin inhibitor (CNI) therapy to everolimus, compared to continuing a standard CNI regimen.

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          Author and article information

          Journal
          Clin. Nephrol.
          Clinical nephrology
          0301-0430
          0301-0430
          Jan 2015
          : 83
          : 1
          Affiliations
          [1 ] Department of Nephrology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Department of Nephrology and Transplantation Medicine, Westpfalz- Klinikum, Kaiserslautern, Department of Nephrology, Heidelberg University Hospital, Heidelberg, Department of Nephrology and Hypertensiology, Hannover Medical School, Hannover, Department of Transplantation, Division of Internal Medicine and Nephrology, Charité Universitätsmedizin Berlin, Campus Virchow, Berlin, Department of Nephrology, University Hospital Essen, University of Duisburg-Essen, Essen, Department of Internal Medicine D, Transplant Nephrology, University of Münster, Münster, Novartis Pharma GmbH, Nuernberg, Department of Nephrology, Medical Clinic Köln-Merheim, Cologne, Germany, and APOLLO Study Group.
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