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      Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study.

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          Abstract

          Between October, 2013, and April, 2014, French Polynesia experienced the largest Zika virus outbreak ever described at that time. During the same period, an increase in Guillain-Barré syndrome was reported, suggesting a possible association between Zika virus and Guillain-Barré syndrome. We aimed to assess the role of Zika virus and dengue virus infection in developing Guillain-Barré syndrome.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          1474-547X
          0140-6736
          Apr 9 2016
          : 387
          : 10027
          Affiliations
          [1 ] Unit of Emerging Infectious Diseases, Institut Louis Malardé, Papeete, Tahiti, French Polynesia.
          [2 ] Institut Pasteur, Emerging Diseases Epidemiology Unit, Paris, France.
          [3 ] Service de Réanimation Polyvalente, Centre Hospitalier de Polynésie Française, Tahiti, French Polynesia.
          [4 ] Clinical Laboratory, Centre Hospitalier de Polynésie Française, Tahiti, French Polynesia.
          [5 ] Institut Pasteur, Laboratory for Urgent Responses to Biological Threats, Paris, France; Unit Environment and Infectious Risks, Institut Pasteur, Paris, France.
          [6 ] Service de neurologie, Centre Hospitalier de Polynésie Française, Papeete, Tahiti, Polynésie Française.
          [7 ] Direction de la Santé, Bureau de Veille Sanitaire, Papeete, French Polynesia.
          [8 ] Service de santé des forces armées, Papeete, French Polynesia.
          [9 ] Unit Environment and Infectious Risks, Institut Pasteur, Paris, France.
          [10 ] Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
          [11 ] Department of Immunology, Laboratory of Immunochemistry & Autoimmunity, Pitié-Salpêtrière Hospital (AP-HP), Paris, France.
          [12 ] University of Reunion Island, La Reunion, France.
          [13 ] Département de Neurophysiologie, Pitié-Salpêtrière Hospital (AP-HP), Paris, France.
          [14 ] Institut Pasteur, Emerging Diseases Epidemiology Unit, Paris, France; Conservatoire National des Arts et Métiers, Paris, France; Institut Pasteur, Centre for Global Health Research and Education, Paris, France. Electronic address: fontanet@pasteur.fr.
          S0140-6736(16)00562-6
          10.1016/S0140-6736(16)00562-6
          26948433
          Copyright © 2016 Elsevier Ltd. All rights reserved.

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