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      A naturally occurring nanomaterial from the Sundew (Drosera) for tissue engineering.

      Bioinspiration & biomimetics
      Adhesives, chemistry, Animals, Biocompatible Materials, Biological Products, Cell Adhesion, physiology, Cell Culture Techniques, methods, Cell Proliferation, Cell Survival, Drosera, Humans, Materials Testing, Nanostructures, PC12 Cells, Polysaccharides, Rats, Tissue Engineering

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          Abstract

          In recent years advances have been made in the design of novel materials for tissue engineering through the use of polysaccharides. This study evaluated the ability of a naturally secreted polysaccharide adhesive from the Sundew (Drosera capensis) as a support for cell growth. The Sundew adhesive has several advantages including its high elasticity and antibiotic nature. By coating glass cover slips with the Sundew adhesive, a network of nanofibers was generated that was capable of promoting attachment and differentiation of a model neuronal cell line, PC-12. We also demonstrated the potential of this material for repairing bone and soft tissue injuries, by testing attachment of osteoblasts and endothelial cells. Finally, it was determined that the Sundew biomaterial was stable through testing by atomic force microscopy and prolonged cell growth. This work has proven the capabilities of using a nanomaterial derived from the Sundew adhesive for the purpose of tissue engineering.

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