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      Low grade multiple myeloma that presented as a labial swelling -- a case report.

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      British dental journal

      Springer Nature America, Inc

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          Abstract

          Myeloma is a disease of the bone marrow in which there is malignant proliferation of plasma cells. Myeloma is usually associated with the accumulation of a monoclonal immunoglobulin or light chains in plasma and subsequently an increase in light chains in the urine (Bence-Jones proteins). Renal failure can occur and bone destruction in the axial skeleton may ensue with pain and fractures. Amyloidosis associated with multiple myeloma is a relatively common finding. The most frequently reported oral sign of amyloidosis is macroglossia. There are numerous cases in the literature of amyloid deposition in tongues related to multiple myeloma. However, none of these cases describe amyloid deposition surrounding arteries in the oral cavity. We therefore report a case of an innocuous lower labial swelling, which subsequently led to the diagnosis of amyloid deposition surrounding an artery, the cause of which was later shown to be multiple myeloma.

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          Author and article information

          Journal
          Br Dent J
          British dental journal
          Springer Nature America, Inc
          0007-0610
          0007-0610
          Oct 08 2005
          : 199
          : 7
          Affiliations
          [1 ] 1S. Ariyaratnam, Specialist in Oral Medicine and Surgical Dentistry, Unit of Oral Medicine, University Dental Hospital of Manchester, Manchester, M15 6FH, UK. senathirajah.ariyaratnam@man.ac.uk
          Article
          4812742
          10.1038/sj.bdj.4812742
          16215569

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