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      Empleo de la toxina botulínica tipo a en el tratamiento del espasmo hemifacial

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          Abstract

          Los trastornos neuromusculares son afecciones que alteran la vida de cualquier persona, movimientos musculares incontrolados que causan molestias e interfieren en la rutina diaria. Esta revisión bibliográfica se ha llevado a cabo con la finalidad de relacionar uno de los agentes químicos más populares en la actualidad para uso estético, la Toxina Botulínica (Botox), con el tratamiento de una entidad que necesita ser tratada más allá de las banalidades de la belleza, como lo es el Espasmo Hemifacial (EHF). Son las mujeres de la 5 década de la vida quienes tienen el mayor riesgo de sufrir esta enfermedad que afecta a los músculos inervados por el nervio facial, con una incidencia de 7.4 a 14.5 casos por cada 100.000 habitantes. Estos pueden ser tratados con varias alternativas terapéuticas, pero es la Toxina Botulínica una de las más usadas, produciendo relajación en el punto exacto del músculo donde se inyecta, con el beneficio de no interferir en la trasmisión de los impulsos nerviosos, sin embargo uno de sus efectos colaterales más destacados es el botulismo, si se administra a altas dosis. Las opciones para tratar una patología pueden ser innumerables, lo importante es analizar la severidad del caso, el factor riesgo-beneficio, las condiciones sistémicas del paciente y la efectividad, duración y costo del tratamiento

          Translated abstract

          The neuromuscular disorders are a group of conditions that affect the nerves that control the voluntary muscles and can interfere with the activities of daily living of any given person. One of these disorders is a condition known as Hemifacial Spam (HFS) which is characterized by frequent involuntary contractions of the ipsilateral muscles innervated by the facial nerve (seventh cranial nerve). This condition more frequently affects women in the fifth decade of life and its incidence among the general population is 7.4 to 14.5 cases per 100.000 person/years. One of the most common therapeutic approaches for this condition is the use of Botulinum toxin (commonly known as Botox). This toxin works by causing the relaxation of the injected muscle reducing the abnormal contractions, though if administered in higher doses than recommended, this therapy could cause a form of botulism.: This toxin produces the paralysis of the myoneural junction causing a neuromuscular blocking effect and reducing abnormal muscle contraction. The purpose of this review is to evaluate the effects of the Botulinum toxin in the treatment of FHS, its effectiveness, side effects, duration and the risk benefits of this therapy

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          Most cited references 12

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          Concerning the mechanism of trigeminal neuralgia and hemifacial spasm.

           R. Gardner (1962)
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            [Indications and management of botulinum toxin].

            Botulinus toxin (BTX) is the most potent biological toxin yet known. It is produced by Clostridium botulinium, a Gram positive bacteria.
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              Espasmo hemifacial

               K McCoy (2020)
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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                aov
                Acta Odontológica Venezolana
                Acta odontol. venez
                Facultad de Odontología -UCV (Caracas )
                0001-6365
                March 2010
                : 48
                : 1
                : 115-120
                Affiliations
                [1 ] UCV
                [2 ] UCV
                [3 ] UCV
                [4 ] UCV
                Article
                S0001-63652010000100018

                http://creativecommons.org/licenses/by/4.0/

                Product
                Product Information: website
                Categories
                DENTISTRY, ORAL SURGERY & MEDICINE

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