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      Tiotropium + olodaterol shows clinically meaningful improvements in quality of life.

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          Abstract

          Tiotropium + olodaterol improves lung function and symptoms compared to monotherapies in chronic obstructive pulmonary disease (COPD). The OTEMTO 1 and 2 studies investigated the effects of tiotropium + olodaterol on lung function and health-related quality of life compared to placebo in patients with moderate to severe COPD.

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          Author and article information

          Journal
          Respir Med
          Respiratory medicine
          1532-3064
          0954-6111
          Oct 2015
          : 109
          : 10
          Affiliations
          [1 ] The Medicines Evaluation Unit, Manchester, UK. Electronic address: dsingh@meu.org.uk.
          [2 ] Pulmonary Research Institute of Southeast Michigan, Livonia, MI, USA.
          [3 ] Krankenhaus der Elisabethinen, Linz, Austria.
          [4 ] Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany.
          [5 ] Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, USA.
          [6 ] Morgantown Pulmonary Associates, Morgantown, WV, USA.
          [7 ] Lungen- und Bronchialheilkunde, Koblenz, Germany.
          [8 ] Department of Respiratory Medicine and Allergology, Lund University, Lund, Sweden.
          Article
          S0954-6111(15)30034-2
          10.1016/j.rmed.2015.08.002
          26320402
          Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

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