• Record: found
  • Abstract: found
  • Article: not found

Lactobacillus plantarum OLL2712 regulates glucose metabolism in C57BL/6 mice fed a high-fat diet.

Journal of nutritional science and vitaminology

blood, Adipose Tissue, metabolism, Animals, Blood Glucose, Cholesterol, Diet, High-Fat, Fatty Acids, Nonesterified, Insulin, Interleukin-1beta, Lactobacillus plantarum, Lipid Metabolism, physiology, Male, Mice, Mice, Inbred C57BL, Obesity, Probiotics, RNA, Messenger, Triglycerides

Read this article at

      There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


      The aim of the present study was to determine the effect of oral administration of Lactobacillus plantarum OLL2712 (L. plantarum OLL2712) on glucose and lipid metabolism in mice with high-fat diet-induced obesity. Mice that had been administered 10(9) cfu heat-killed L. plantarum OLL2712 for 12 wk showed significant reduction of blood glucose levels in response to insulin. Furthermore, mRNA expression of interleukin-1β in adipose tissue and serum levels of nonesterified fatty acids in mice administered L. plantarum OLL2712 were significantly lower than those in control mice. These results indicate that L. plantarum OLL2712 regulates glucose metabolism.

      Related collections

      Author and article information



      Comment on this article