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Colorimetric detection of multidrug-resistant or extensively drug-resistant tuberculosis by use of malachite green indicator dye.

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      Abstract

      The malachite green microtube (MGMT) susceptibility assay was performed directly on sputum specimens (n = 80) and indirectly on Mycobacterium tuberculosis clinical isolates (n = 60). The technique is based on the malachite green dye, which changes color in response to M. tuberculosis growth. The MGMT assay is simple and rapid and does not require expensive instruments.

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      Affiliations
      [1 ] Mycobacteriology Research Centre, National Research Institute of Tuberculosis and Lung Disease, Shaheed Bahonar Ave., Darabad, Tehran 19556, PO Box 19575/154, Iran. pfarnia@hotmail.com
      Journal
      J. Clin. Microbiol.
      Journal of clinical microbiology
      1098-660X
      0095-1137
      Feb 2008
      : 46
      : 2
      18094133
      JCM.01435-07
      10.1128/JCM.01435-07
      2238113

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