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      Epigenetic mechanisms regulating learning and long-term memory.

      International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
      Animals, Brain, physiology, DNA Methylation, Epigenesis, Genetic, Histones, metabolism, Humans, Learning, Memory, Long-Term, MicroRNAs, Neuronal Plasticity

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          Abstract

          A balance between rapid, short lived, neuronal responses and prolonged ones fulfill the biochemical and cellular requirements for creating a molecular memory. I provide an overview of epigenetic mechanisms in the brain and discuss their impact on synaptic plasticity, cognitive functions, and discuss a recent example of how they can contribute to neurodegeneration and the cognitive decline associated with Alzheimer's disease. Copyright © 2012 ISDN. Published by Elsevier Ltd. All rights reserved.

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          Journal
          23142272
          10.1016/j.ijdevneu.2012.10.110

          Chemistry
          Animals,Brain,physiology,DNA Methylation,Epigenesis, Genetic,Histones,metabolism,Humans,Learning,Memory, Long-Term,MicroRNAs,Neuronal Plasticity

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