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      Neurohypophyseal Peptides and Psychopathology

      Hormone Research in Paediatrics

      S. Karger AG

      Anorexia, Bulimia, Depression, Neurohypophyseal peptides, Oxytocin, Schizophrenia, Vasopressin

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          Abstract

          The study of neurohypophyseal peptides in various neuropsychiatric disorders is of interest because the hypothalamo-posterior pituitary axis is directly influenced by modifications of central neurotransmitter metabolism involved in behaviour control. Moreover, the main neurohypophyseal peptides, namely vasopressin and oxytocin, are themselves capable of modifying behaviour. In this paper the author discusses current understanding of the anatomy and physiology of the main central vasopressinergic and oxytocinergic pathways, followed by a description of the principal actions of exogenously administered vasopressin and oxytocin on human behaviour. Finally, modifications of endogenous neurohypophyseal function encountered in different pathological states are described.

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          Author and article information

          Journal
          HRE
          Horm Res Paediatr
          10.1159/issn.1663-2818
          Hormone Research in Paediatrics
          S. Karger AG
          978-3-8055-5670-5
          978-3-318-01974-2
          1663-2818
          1663-2826
          1992
          1992
          03 December 2008
          : 37
          : Suppl 3
          : 16-21
          Affiliations
          Endocrinology Department, University of Liège, Belgium
          Article
          182396 Horm Res 1992;37:16–21
          10.1159/000182396
          1427637
          © 1992 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 6
          Categories
          Session I: Neuroendocrinology

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