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      The Role of Curcumin Administration in Patients with Major Depressive Disorder: Mini Meta-Analysis of Clinical Trials : Clinical Effect of Curcumin on Depression

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      Phytotherapy Research

      Wiley-Blackwell

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          Meta-analysis in clinical trials

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            Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication.

            Little is known about the general population prevalence or severity of DSM-IV mental disorders. To estimate 12-month prevalence, severity, and comorbidity of DSM-IV anxiety, mood, impulse control, and substance disorders in the recently completed US National Comorbidity Survey Replication. Nationally representative face-to-face household survey conducted between February 2001 and April 2003 using a fully structured diagnostic interview, the World Health Organization World Mental Health Survey Initiative version of the Composite International Diagnostic Interview. Nine thousand two hundred eighty-two English-speaking respondents 18 years and older. Twelve-month DSM-IV disorders. Twelve-month prevalence estimates were anxiety, 18.1%; mood, 9.5%; impulse control, 8.9%; substance, 3.8%; and any disorder, 26.2%. Of 12-month cases, 22.3% were classified as serious; 37.3%, moderate; and 40.4%, mild. Fifty-five percent carried only a single diagnosis; 22%, 2 diagnoses; and 23%, 3 or more diagnoses. Latent class analysis detected 7 multivariate disorder classes, including 3 highly comorbid classes representing 7% of the population. Although mental disorders are widespread, serious cases are concentrated among a relatively small proportion of cases with high comorbidity.
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              Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

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                Author and article information

                Journal
                Phytotherapy Research
                Phytother. Res.
                Wiley-Blackwell
                0951418X
                February 2016
                February 27 2016
                : 30
                : 2
                : 175-183
                10.1002/ptr.5524
                © 2016

                http://doi.wiley.com/10.1002/tdm_license_1.1

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                Self URI (article page): http://doi.wiley.com/10.1002/ptr.5524

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