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Ventriculoarterial Coupling during Low-Level Exercise Testing after Myocardial Infarction
Abstract
To evaluate the change of ventriculoarterial coupling during low-level exercise in patients after myocardial infarction, the ratio of systolic blood pressure to left ventricular end-systolic volume (P/V ratio) and the ratio of systolic blood pressure to stroke volume (effective arterial elastance) were investigated using radionuclide angiography in 73 consecutive patients with a negative predischarge exercise test. The patients were divided into three groups according to their resting left ventricular ejection fraction: group A (n = 12) ≧ 60%; group B (n = 32) 41-59%; group C (n = 29) ≤ 40%. The ejection fraction increased significantly during exercise in all three groups. There was no significant difference in the change of the P/V ratio during exercise between groups A and B, but it was significantly smaller in group C. The effective arterial elastance increased during exercise in group A, did not change in group B, and decreased in group C. Thus, the augmentation of myocardial contractility was an important factor related to the increase in ejection fraction during exercise in patients with normal or slightly reduced cardiac function, whereas the decrease in effective arterial elastance was important in patients with poor cardiac function.
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175968 Cardiology 1993;83:190–196Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.