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Randomized trial of radiotherapy versus concurrent chemoradiotherapy followed by adjuvant chemotherapy in patients with American Joint Committee on Cancer/International Union against cancer stage III and IV nasopharyngeal cancer of the endemic variety.
Joseph Wee
1 ,
Eng Huat Tan ,
Bee Choo Tai ,
Hwee Bee Wong ,
Swan Swan Leong ,
Terence Tan ,
Eu Tiong Chua ,
Edward Yang ,
Khai Mun Lee ,
Kam Weng Fong ,
Hoon Seng Khoo Tan ,
Kim Shang Lee ,
Susan Loong ,
Vijay Sethi ,
Eu Jin Chua ,
David Machin
Sep 20 2005
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Abstract
The Intergroup 00-99 Trial for nasopharyngeal cancer (NPC) showed a benefit of adding chemotherapy to radiotherapy. However, there were controversies regarding the applicability of the results to patients in endemic regions. This study aims to confirm the findings of the 00-99 Trial and its applicability to patients with endemic NPC.