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      Randomized trial of radiotherapy versus concurrent chemoradiotherapy followed by adjuvant chemotherapy in patients with American Joint Committee on Cancer/International Union against cancer stage III and IV nasopharyngeal cancer of the endemic variety.

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          Abstract

          The Intergroup 00-99 Trial for nasopharyngeal cancer (NPC) showed a benefit of adding chemotherapy to radiotherapy. However, there were controversies regarding the applicability of the results to patients in endemic regions. This study aims to confirm the findings of the 00-99 Trial and its applicability to patients with endemic NPC.

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          Author and article information

          Journal
          J Clin Oncol
          Journal of clinical oncology : official journal of the American Society of Clinical Oncology
          American Society of Clinical Oncology (ASCO)
          0732-183X
          0732-183X
          Sep 20 2005
          : 23
          : 27
          Affiliations
          [1 ] Department of Radiation Oncology, National Cancer Center, Singapore 169610, Republic of Singapore. trdwts@nccs.com.sg
          Article
          23/27/6730
          10.1200/JCO.2005.16.790
          16170180
          2eb108e5-8dfa-4786-be38-b05d105add15
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