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      Blood Fibrinolytic Activity in Skin Diseases


      Journal of Vascular Research

      S. Karger AG

      Euglobulinlysis time, Skin disease

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          In a study of a total of 369 patients with skin diseases, decreased blood fibrinolytic activity was found inpatients with herpes simplex, herpes zoster, erythema multi-forme, five out of six patients with chilblain, two out of five patients with Behçet’s syndrome, three out of five patients with polyarteritis nodosa, 40% of patients with erythema nodosum, 43% of patients with psoriasis, 56 % of patients with cutaneous vasculitis, 45 % of the patients with idiopathic Raynauds disease, 54% of patients with venous leg ulcers, 58% of patients with systemic lupus erythematosus, 52% of patients with eczema, 58% of patients with systemic sclerosis and 50% of patients with acne. The possibility that the decreased fibrinolytic activity in the blood may play an important role in the as yet unknown pathogenesis of some of these diseases is suggested.

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          Author and article information

          J Vasc Res
          Journal of Vascular Research
          S. Karger AG
          18 September 2008
          : 7
          : 1
          : 39-43
          Departments of Medicine and Dermatology, Royal Victoria Infirmary and University of Newcastle upon Tyne, Newcastle upon Tyne
          157814 Angiologica 1970;7:39–43
          © 1970 S. Karger AG, Basel

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          Page count
          Pages: 5


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