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      Active bleeding from a periampullary duodenal diverticulum that was difficult to diagnose but successfully treated using hemostatic forceps: a case report

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          Abstract

          Introduction

          Although duodenal diverticula are common, periampullary duodenal diverticula are rare. Periampullary duodenal diverticula are usually asymptomatic and may be difficult to diagnose and treat. However, they may present with massive bleeding, requiring prompt diagnosis.

          Case presentation

          We report the case of a 71-year-old Asian woman with bleeding from a periampullary duodenal diverticulum. She presented with severe anemia and tarry stools. Two examinations using a forward-viewing endoscope did not identify the source of the bleeding. However, examination using a side-viewing endoscope found an exposed bleeding vessel overlying the bile duct within a periampullary diverticulum of the descending part of the duodenum. The bleeding was successfully controlled by using hemostatic forceps.

          Conclusions

          Bleeding periampullary duodenal diverticula are rare, and a bleeding point in the mucosa overlying the bile duct within a large periampullary duodenal diverticulum is very rare. Identification of a bleeding point within a duodenal diverticulum often requires repeated examination and may require the use of a side-viewing endoscope. Use of hemostatic forceps to control bleeding from a periampullary duodenal diverticulum is very rare but, for bleeding lesions overlying the bile duct within a periampullary duodenal diverticulum, is the best way to prevent obstructive jaundice.

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          Most cited references9

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          Review of duodenal diverticula.

          Duodenal diverticula occur in 2-5% of patients undergoing barium studies of the upper intestinal tract. Duodenal diverticula are classified into two types: extraluminal or intraluminal. Usually of little clinical significance, they can cause obstruction, cholelithiasis, ascending cholangitis, ulcers, and hemorrhage, and may perforate. Associated intestinal tract malformations have been reported in 40% of patients with intraluminal duodenal diverticula. Diagnosis is made by endoscopy or upper gastrointestinal series. In symptomatic cases, extraluminal diverticula are amenable to surgery, whereas intraluminal diverticula may be either surgically or endoscopically resected. Imaging of the biliary tree should be performed prior to any intervention.
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            Clinical analysis and literature review of massive duodenal diverticular bleeding.

            A duodenal diverticulum (DD) appears in 2.5% of upper gastrointestinal (UGI) examinations and up to 22% of endoscopic retrograde cholangiopancreaticographies (ERCP) and autopsies. Most of these patients are asymptomatic, but the lesion is occasionally associated with bleeding, inflammation, perforation, obstruction of the duodenum or biliary-pancreatic duct (or both), fistula formation in the bile duct, and bezoar formation inside the diverticulum. A total of 816 patients have undergone ERCP examination at our institution since January 1987, and 100 (12.25%) of them have DD. Seven (7%) patients presented with bloody or tarry stools from massive UGI bleeding followed by shock. Only two could be diagnosed by UGI endoscopy preoperatively. The lesions were demonstrated in angiographic studies in another four cases. However, only one was correctly interpreted and one required reoperation after a correct repeat endoscopic finding. The lesions in the other two patients were identified by thorough exploration during laparotomy. The remaining case was diagnosed by intraoperative endoscopy via pyloroduodenotomy. Six underwent surgical intervention, and one was successfully treated by expectant treatment. Three (50%) had leakage from the duodenotomy but recovered uneventfully with conservative treatment. In conclusion, we believe that DD bleeding is more frequent than usually thought. A high index of suspicion should be raised in cases of UGI bleeding when more obvious and common causes have been excluded by routine endoscopy. Aggressive but careful endoscopic examination combined with accurate angiography can help us diagnose most of the cases preoperatively. Diverticulectomy is an effective surgical procedure, though it is associated with a considerable leakage rate. The morbidity is minimal if we can identify the lesion earlier and evacuate the lesion without delay.
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              Impact of endoscopy in the management of duodenal diverticular bleeding: experience of a single medical center and a review of recent literature.

              Duodenal diverticulum (DD) is a rare cause of upper-GI bleeding. The diagnosis and treatment of DD bleeding (DDB) is challenging. Surgical management was the mainstay of therapy before the 1990s. To evaluate the clinical feature, diagnosis, and management of cases of DDB at our institution and the literature after the first description of endoscopic therapy of this disease. Retrospective single-center clinical review. Primary- and tertiary-care centers. A retrospective study of patients with DDB from January 2000 to January 2005 at Changhua Christian Medical Center. Diagnostic yield and therapy results of endoscopy on DDB. At our institution, from January 2000 to January 2005, a total of 11 patients (4 men and 7 women, mean age 75 years) were found to have DDB. The diverticulum was located in the second portion (n = 10) and the third portion (n = 1). Endoscopy was used as the diagnostic method in all of these cases and as the therapeutic method in 72.73% of these cases. None of our patients experienced recurrent bleeding. The study is limited to the small case number and was retrospective. To our knowledge, this is the first report and the largest series that studied endoscopic management of DDB in the literature. We concluded that endoscopy is useful to diagnose and treat patients with DDB.
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                Author and article information

                Journal
                J Med Case Rep
                J Med Case Rep
                Journal of Medical Case Reports
                BioMed Central
                1752-1947
                2012
                26 October 2012
                : 6
                : 367
                Affiliations
                [1 ]Departments of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, 1750-1 Miki, Kagawa, Kita, 761-0793, Japan
                [2 ]Department of Pharmacology, Faculty of Medicine, Kagawa University, 1750-1 Miki, Kagawa, Kita, 761-0793, Japan
                Article
                1752-1947-6-367
                10.1186/1752-1947-6-367
                3485119
                23101939
                2f1ad039-fe83-4fa9-9de5-790edfa56982
                Copyright ©2012 Nishiyama et al.; licensee BioMed Central Ltd.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 18 July 2012
                : 20 September 2012
                Categories
                Case Report

                Medicine
                side-viewing endoscopy,hemostatic forceps,obscure gastrointestinal bleeding,bleeding periampullary duodenal diverticulum

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