A new genus of the spider family Deinopidae C.L. Koch, 1850 is described from Asia: Asianopis Lin & Li gen. nov., with A. zhuanghaoyuni Lin & Li sp. nov. as the type species. The new genus is divided into two species groups, of which the liukuensis -group includes two species: A. dumogae (Merian, 1911) sp. reval. comb. nov. (♀) and A. liukuensis (Yin, Griswold & Yan, 2002) comb. nov. (♂♀); and the zhuanghaoyuni -group comprises five species: A. celebensis (Merian, 1911) comb. nov. (♂), A. konplong (Logunov, 2018) comb. nov. (♂), A. wangi Lin & Li sp. nov. (♂♀), A. wuchaoi Lin & Li sp. nov. (♂♀), and A. zhuanghaoyuni Lin & Li sp. nov. All previously described species are transferred from Deinopis MacLeay, 1839. Deinopis scrubjunglei Caleb & Mathai, 2014 is treated as a junior synonym of Asianopis liukuensis comb. nov.