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      A Comparative Study on the Effect of Atenolol and Labetalol on Exercise Capacity and Lipid Serum Levels in Essential Hypertension

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          Abstract

          Exercise performance was examined in 30 hypertensive subjects (mean age 42.3 + 5.4 years) in WHO group I–II, allocated to placebo, atenolol and labetalol treatment during a 3 × 12 weeks’ exercise training period. Total work did not show any differences between the placebo and the two treatment periods. Compared to placebo, total cholesterol was reduced by 4.6% (p < 0.04) in the labetalol and 3.1% (NS) in the atenolol period. Systolic and diastolic blood pressure were significantly reduced both at rest (p < 0.01) and during exercise (p < 0.01) in the two drug treatment periods compared to placebo.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          978-3-8055-4710-9
          978-3-318-01616-1
          1660-8151
          2235-3186
          1987
          1987
          05 December 2008
          : 47
          : Suppl 1
          : 135-137
          Affiliations
          aOutpatient Clinic, Rikshospitalet; bDepartment of Clinical Physiology, Ullevål Hospital, and cGlaxo A/S, Oslo, Norway
          Article
          184572 Nephron 1987;47:135–137
          10.1159/000184572
          3320787
          2feff689-22a8-407f-8a57-b4c94f290235
          © 1987 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Page count
          Pages: 3
          Categories
          Poster Session

          Cardiovascular Medicine,Nephrology
          Exercise training,Atenolol,Lipids,Essential hypertension,Labetalol
          Cardiovascular Medicine, Nephrology
          Exercise training, Atenolol, Lipids, Essential hypertension, Labetalol

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